During a period of 2 years we prospectively studied 116 infants up to 8 weeks of age with suspected sepsis. Each infant was assessed clinically before laboratory evaluation for sepsis. Depending upon impression of sepsis, temperature abnormality, micro ESR (mESR), WBC counts and toxic granulations infants were assigned to either high (n = 74) or low (n = 31) risk group for serious bacterial inf...

Campylobacter jejuni is a common cause of bacterial gastroenteritis in most parts of the world. The bacterium has a broad host range and has been isolated from many animals and environments. To investigate shedding patterns and putative effects on an avian host, we developed a colonization model in which a wild bird species, the European Robin Erithacus rubecula, was inoculated orally with C. j...

We evaluated the bactericidal activity of RP 59500 (quinupristin-dalfopristin) against fibrin-platelet clots (FPC) infected with two clinical isolates of Staphylococcus aureus, one constitutively erythromycin and methicillin resistant (S. aureus AW7) and one erythromycin and methicillin susceptible (S. aureus 1199), in an in vitro pharmacodynamic infection model. RP 59500 was administered by co...

Endophytes are microorganisms that live inside the host plant tissues which have novel metabolites exhibiting a variety of biological activities against different pathogens. This study was carried out to isolate endophytic bacteria and fungi from Terminalia arjuna (marutham), Catharanthus roseus (nithyakalyani) and Azadirachta indica (vembu) and to assess their antimicrobial activity against Ps...

Water samples were collected from various sampling sites surrounding the ship building industries in Goa and plated on Zobell marine agar (ZMA), Nutrient agar (NA) and Mineral salt medium agar (MSMA) containing 0.1 mM tributyltin chloride (TBTC). The physicochemical characteristics of the water samples were determined. The total viable counts of bacteria ranged from 58 × 10 cfu/ml in MSMA+TBTC ...

-ASPARAGINASE (L-ASNase) has been widely used as a therapeutic agent in the treatment for various lymphoblastic leukemia diseases. This study aimed to isolate and purify local bacterial isolates that are capable of producing L-ASNase, so 150 bacterial isolates from the Nile River where isolated, purified and their ability to produce L-ASNase was assessed. Among these isolates, 32 bacterial isol...

in this study, zinc oxide nanoparticles (znonps) were synthesized by chemical method and their antibacterial efficiency against a clinical isolate of staphylococcus aureus was studied. the zinc oxide nanoparticles have shown a commendable inhibition effect on the growth of most notorious bacterial pathogen s.aureus. the nanoparticles size and shapes were characterized by transmission electron m...

the antagonistic effects of rhizobium spp. isolates against rhizoctonia solani (ag-4), the causal agent of bean damping-off were compared with each other in either of the in vitro and in vivo conditions. also their potential to produce such secondary antifungal metabolites as hcn, siderophore and protease were evaluated. the results indicated that, isolate rh3 reduced mycelial growth of r. sola...

BACKGROUND Early recognition and prompt and appropriate antibiotic treatment can significantly reduce mortality from serious bacterial infections (SBI). The aim of this study was to evaluate the utility of five markers of infection: C-reactive protein (CRP), procalcitonin (PCT), soluble triggering receptor expressed on myeloid cells-1 (sTREM-1), CD163 and high mobility group box-1 (HMGB1), as m...

Traditional risk factors are not adequate for predicting serious bacterial infection (SBI) in febrile infants. The purpose of this study was to evaluate the diagnostic value of the plasma level of soluble form of triggering receptor expressed on myeloid cells-1 (sTREM-1) in predicting SBI in febrile infants less than 3 months old. Forty-four febrile infants less than 3 months old with clinical ...