introduction: autosomal dominant polycystic kidney disease (adpkd) is one of the most common genetic kidney disorders with the incidence of 1 in 1,000 births. adpkd is genetically heterogeneous with two genes identified: pkd1 (16p13.3, 46 exons) and pkd2 (4q21, 15 exons). eighty five percent of the patients with adpkd have at least one mutation in the pkd1 gene. genetic studies have demonstrate...

World Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD) in childhood differs from that in adults, as the largest diagnostic group among children includes congenital anomalies and inherited disorders, with glomerulopathies and kidney disease in the setting of diabetes being rela...

as the world’s population continues to age, practitioners encounter increasing numbers of older patients with end-stage renal disease (esrd) who require renal replacement therapy (rrt). conservative management may be considered in older patients and has been shown to offer comparable survival rates and hospital-free days to rrt patients. at present, for those who choose rrt, hemodialysis is the...

conclusions spironolactone combined with aceis or arbs leads to reduction of proteinuria in chronic kidney disease and therefore reduction of progression of the disease. objectives the study was designed to assess the effects of spironolactone as the aldosterone antagonist combined with acei or arb drugs to reduce proteinuria in chronic kidney disease to prevent its progression. patients and me...

study of a family with autosomal dominant polycystic kidney diseases (adpkd) in five generations, including 96 healthy and 47 affected individuals, has been carried out in tehran. investigation on individuals, including final diagnoses by clinical findings, sonography, radiography and laboratory results, have lead to the completion of genealogical chart of the family. the affected individuals h...

context hepatitis b vaccination of hemodialysis patients is performed all over the world. there are also recommendations from world health organizations to vaccinate patients with chronic kidney disease (ckd) prior dialysis commencement, but the implementation of a hepatitis b vaccination program is less common and not well organized. evidence acquisition this review article summarizes data ind...

objective(s):micrornas (mirnas) are small non-coding rna molecules that regulate gene expression. they have important roles in kidney development, homeostasis and disease, and participate in the onset and progression of tubulointerstitial sclerosis and end-stage glomerular lesions that occur in various forms of chronic kidney disease (ckd). in the present study, we elucidated the role of micror...

results the results showed that the means of patients' expectations were more than their perceptions of the quality of provided services in all dimensions, which indicated that there were gaps in all dimensions. the highest and lowest means of negative gaps were related to empathy (-0.52 ± 0.48) and tangibility (-0.29 ± 0.51). in addition, among the studied patients' demographic characteristics...

background: zeolites containing silver ion, in combination with synthetic fibers, show antibacterial activity. objectives: the purpose of this study was to use silver zeolite indirectly as antimicrobial agents to control streptococcus iniae infection which recently has caused disease in some of rainbow trout farms in iran. methodes: in this context polyurethane foams containing silver zeolite (...