there is strong evidence that two cerebral hemispheres are differentially involved in emotional memory and that amygdala is a key subcortical structure for emotional experience. the present research investigated the possible involvement of lateralization of basolateral amygdala (bla) and central amygdala (cea) in place avoidance memory. for this purpose, male long-evans rats (280-320 g) were im...

introduction: it has been shown that administration of win55,212-2, a cannabinoid receptor agonist, into the basolateral amygdala (bla), dose-dependently increases the thermal latency to withdrawal in the tail-.ick test and decreases pain related behaviors in both phases of the formalin test. recent human and animal imaging data suggest that the nucleus accumbens (nac) is an important neural su...

The involvement of the basolateral and the medial amygdala in fear conditioning was evaluated using different markers of neuronal activation. The method described here is a combination of cytochrome oxidase (CO) histochemistry and c-Fos immunocytochemistry on fresh frozen brain sections. Freezing behavior was used as an index of auditory and contextual fear conditioning. As expected, freezing s...

The amygdala is under inhibitory control from the cortex through the activation of local GABAergic interneurons. This inhibition is greatly diminished during heightened emotional states due to dopamine release. However, dopamine excites most amygdala interneurons, suggesting that this dopaminergic gate may be mediated by an unknown subpopulation of interneurons. We hypothesized that this gate i...

The stress hormone corticosterone increases the amplitude of the slow afterhyperpolarization in CA1 pyramidal neurons, without affecting resting membrane potential, input resistance or action potential characteristics. We here examined how corticosterone affects these properties in the basolateral amygdala. In the amygdala, corticosterone does not change the afterhyperpolarization amplitude, no...

The goal of this work was to test the involvement of the central nucleus and basolateral complex of the amygdala in fear conditioning, using auditory and visual conditioned stimuli (CSs). The acoustic startle reflex in rats was used as the behavioral index of conditioning because startle is reliably enhanced in the presence of a conditioned stimulus (CS) previously paired with a footshock. Init...

introduction: the claustrum interconnects with the allocortical and neocortical regions and also projects to the hippocampus and the amygdala. .the role of claustrum in the complex partial seizure is not clear. thus in this study the effect of amygdala lesion on anterior claustrum kindled seizures in rat were investigated. methods: male wistar rats, weighting 250-300 g, were received dc current...

Activation of adrenoreceptors modulates synaptic transmission in the basolateral amygdala. Here, we investigated the effects of alpha2-adrenoreceptor activation on long-term depression and long-term potentiation in an in vitro slice preparation of the mouse basolateral amygdala. Field potentials and excitatory postsynaptic currents were evoked in the basolateral amygdala by stimulating the late...

Introduction: The claustrum interconnects with the allocortical and neocortical regions and also projects to the hippocampus and the amygdala. .The role of claustrum in the complex partial seizure is not clear. Thus in this study the effect of amygdala lesion on anterior claustrum kindled seizures in rat were investigated. Methods: Male Wistar rats, weighting 250-300 g, were received DC curren...

Amygdala is widely known as a critical neural hub for modulating negative emotions such fear and anxiety. Recent studies have shown that the basolateral amygdala (BLA) has reciprocal innervation, which plays an important role in regulating social interaction associative memory. However, connectivity pattern functional of contralateral projecting BLA neurons stress-related anxiety are not fully ...