Metastatic disease is linked to TERT promoter mutations in conjunctival melanomas (CM). Both and ATRX are associated with faulty telomere maintenance. This study aimed determine the prognostic value of loss melanocytic lesions. Eighty-six lesions from Rotterdam Ocular Melanoma Study group were collected. status determined using immunohistochemical staining molecular diagnostics, respectively. N...

An animal with a parasite is not likely to behave like a similar animal without that parasite. This is a simple enough concept, one that is now widely recognized as true, but if we move beyond that statement, the light that it casts on behavior fades quickly: the world of parasites, hosts and behavior is shadowy, and boundaries are ill-defined. For instance, at first glance, the growing list of...

Should captive animals be excluded from phylogenetic, morphological or behavior studies as they are “atypical” and do not represent the natural state? [1]. Domestication has been associated with paedomorphosis, with alterations of appearance including facial “simplification,” subcutaneous fat accumulation [2]. Brain and body size and character are altered [3]. Genetic variability is reduced [3]...

Fluctuations in ovarian hormones throughout the estrous cycle may underlie sex differences in behavior. In this study, estrogen plus progesterone were coadministered at different ratios to determine whether the interaction of those hormones during the estrous cycle contributes to cocaine-induced alterations in behavior. Before cocaine (15 mg/kg) or saline administration, ovariectomized female r...

This paper reports an experiment conducted to evaluate the effects of alterations in the terms of repayments to depositors following a liquidity suspension as well as the effect of alterations in the publicity of information about withdrawal behavior on the fragility of distressed banks. Results indicate that a “tough” renegotiation stance, e.g. of protecting depositors who maintain their money...