toxoplasmosis is a protozoal infection caused by toxoplasma gondii. toxoplasmosis produce severe damage in patients who are immunosuppresed. in those who are immunosupressed, latent infection can be reactivated resulting in acute disseminating disease. betamethasone is a synthetic glycocorticoid, used as an anti-inflamatory and immunosuppressant in a wide variety of disorders.the aim of this st...

Background: There are strong evidences suggesting the secretion of different cytokines in cervical fluid during preterm labor. Betamethasone is widely administered for several reasons in preterm conditions. Objective: To Investigate the possible effect of betamethasone on endocervical cytokine concentration of women at risk of preterm labor. Methods: In a randomized clinical trial of 80 prime-g...

Prenatal exposure to glucocorticoids is associated with alterations in fetal growth and endocrine function. However, few studies have examined the effects of clinically relevant doses of glucocorticoids on postnatal hypothalamic-pituitary-adrenal (HPA) function. To determine the effects of maternal or fetal betamethasone administration (0.5 mg/kg maternal or estimated fetal weight) on postnatal...

OBJECTIVES This study compared the beneficial and adverse neonatal effects of a single versus repeated courses of antenatal betamethasone. SETTING Tertiary care hospital DESIGN Open labeled, randomized controlled trial. PARTICIPANTS Pregnant women (26-33 weeks) at risk of preterm delivery, who received one course of antenatal betamethasone and remained undelivered for 7 days. Those with u...

BACKGROUND Postoperative sore throat, cough, and hoarseness of voice though minor sequelae after general tracheal anaesthesia can be distressing to the patient. METHODS This prospective, randomized, double blind, controlled study compares the incidence of postoperative sore throat, cough, and hoarseness of voice after general tracheal anaesthesia when applying betamethasone gel (betamethasone...

Background: Avena sativa, a well-known herbal medicine; has been used in various skin diseases such as eczema, burn and pruritus. Objective: The objective of this study was to evaluate the effect of this herbal medicine for treatment of chronic pruritus in Sulfur Mustard (SM) exposed patients. Methods: Veterans who referred to Baghiat-Allah dermatologic clinic for itching problems were examin...

Betamethasone (BM) receptor cncentrations in the liver cytosol from adrenalectomized rats treated with 0. 2 and 2 mg BM were measured and correlated with BM concentrations in the serum and liver. The BM levels in the serum, liver cytosol and nuclei changed in a parallel fashion. One hr after BM administration, serum BM reached a peak, then decreased gradually and was undetectable at 24-48 hr. T...

OBJECTIVE Inadequate postoperative pain relief after cesarean section can increase complications. In this study, we evaluated the effect of intrathecal betamethasone as an adjunct to bupivacaine on postoperative pain in patients undergoing cesarean section. METHODOLOGY Ninety-nine patients undergoing cesarean section were assigned to one of three groups. Group 1 (Control) patients received in...