objective: testicular cell transplantation has been widely used to investigate the restoration of fertility in rodent models. in this research we apply transplantation as a treatment method in the cryptorchid model and compare this method with orchidopexy, which is the routine treatment for this problem. we studied the controversial effects of treatment on the number of germ cells and other mor...

This paper reports simultaneous occurrence of cryptorchidism and testicular tumor in three brothers within a single family. Two of the brothers had seminoma and the third brother had embryonal carcinoma. Tumor markers such as alpha fetoprotein, assay for beta subunit of human chorionic gonadotrophic hormone, and carcinoembryonic antigen were all negative. The simultaneous occurrence of familial...

Cryptorchidism is the most frequent defect of the male urogenital tract at birth. It represents a risk factor for primitive testiculopathy associated with long-term complications (infertility, testicular neoplasia, and hormonal changes). An only consensus exists: "children with bilateral cryptorchidism who are not treated in early age are certainly set to become infertile". The majority of Auth...

Joong Geun Lee, Sang Hyub Lee, Seung Hyun Jeon, Jin Il Kim, Koo Han Yoo From the Department of Urology, School of Medicine, Kyung Hee University, Seoul, Korea Silver-Russel syndrome (SRS) is a disorder present at birth that involves poor growth, low birth weight, differences in the size of the two sides of the body, and genital anomalies. The diagnosis is based on distinct prenatal growth restr...

A boy who had previously had a cleft lip and palate repaired and bilateral orchiopexies presented at 16 years of age with delayed puberty. Isolated gonadotrophin deficiency and testicular hyporesponsiveness to human chorionic gonadotrophin were found. The possibility of bilateral cryptorchidism due to gonadotrophin deficiency should be considered in boys with either cleft lip or palate, or both.

INTRODUCTION Persistent Mullerian duct syndrome (PMDS) is a rare type of male pseudohermaphroditism. Transverse testicular ectopia (TTE) is characterized by one testis moving to the opposite side and both testes traversing the same inguinal canal. CASE PRESENTATION An 11-month-old boy presented with bilateral cryptorchidism. The left testis was not palpable; the right testis was canalicular w...

The ultimate goal in the treatment of cryptorchidism is to achieve normal fertility. However, in a substantial number of cryptorchid males, early and apparently successful orchidopexy does not improve fertility as it does not address the underlying pathophysiological cause, namely, the impaired transformation of gonocytes into Ad spermatogonia. It is important to realize that over half the pati...