نتایج جستجو برای: bilateral wilms

تعداد نتایج: 85842  

Journal: :Hematology/oncology and stem cell therapy 2016
Wissam Rabeh Samir Akel Toufic Eid Samar Muwakkit Miguel Abboud Hassan El Solh Raya Saab

OBJECTIVE/BACKGROUND Management of Wilms tumor (WT) in children depends on a multidisciplinary approach to treatment, and outcomes have significantly improved as reported by cooperative group clinical trials. Here, we review the clinical outcomes of patients with WT and identify challenges and barriers encountered in multidisciplinary management outside of cooperative clinical trials. METHODS...

2003

Normal Anatomy of the Urinary Prune-Belly Syndrome/ 289 Tract/ 255 Megacystis-Microcolon-intestinal Bilateral Renal Agenesis/ 259 Hypoperistalsis Syndrome/ 291 Infantile Polycystic Kidney Congenital Mesoblastic Disease/ 266 Nephroma/ 292 Adult Polycystic Kidney Disease/ 268 Wilms’ Tumor/ 293 Multicystic Kidney Disease/ 270 Normal Anatomy of the Adrenal Ureteropelvic junction Glands/ 295 Obstruc...

2012
Richard H. Scott Anne Murray Linda Baskcomb Clare Turnbull Chey Loveday Reem Al-Saadi Richard Williams Fin Breatnach Mary Gerrard Juliet Hale Janice Kohler Pablo Lapunzina Gill A. Levitt Sue Picton Barry Pizer Milind D. Ronghe Heidi Traunecker Denise Williams Anna Kelsey Gordan M. Vujanic Neil J. Sebire Paul Grundy Charles A. Stiller Kathy Pritchard-Jones Jenny Douglas Nazneen Rahman

Somatic defects at five loci, WT1, CTNNB1, WTX, TP53 and the imprinted 11p15 region, are implicated in Wilms tumor, the commonest childhood kidney cancer. In this study we analysed all five loci in 120 Wilms tumors. We identified epigenetic 11p15 abnormalities in 69% of tumors, 37% were H19 epimutations and 32% were paternal uniparental disomy (pUPD). We identified mutations of WTX in 32%, CTNN...

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