The biliary tree consists of intrahepatic and extrahepatic bile ducts and is lined by biliary epithelial cells (or cholangiocytes). There are also peribiliary glands around the intrahepatic large bile ducts and extrahepatic bile ducts. The biliary tree is a conduit of bile secreted by hepatocytes and biliary epithelial cells and also of the peribiliary glands and has several physiological roles...

Intrahepatic cholangiocarcinoma (iCCA) can originate from the large bile duct group (segment ducts and area ducts), small (septal interlobular terminal (bile ductules canals of Hering) intrahepatic biliary tree, which be histopathological corresponding to type iCCA, iCCA with ductal plate malformation pattern, cholangiolocarcinoma, respectively. The challenge in pathological diagnosis above sub...

Bile ducts are often analyzed for diagnosis of liver disease, and are an important histopathological structure in liver tissues. We presents an automatic approach to their detection: cell nuclei and other artifacts are detected using a Hough technique; epithelial nuclei are then classified from these objects; inner areas of bile ducts are constructed by iterative voting based on positions of th...

BACKGROUND/AIMS Breast cancer is the most common tumor in women and the first cause of death for malignancy in the female population. Bile ducts are not among the common sites of metastasis from breast cancer; few cases of obstructive jaundice due to metastatic breast cancer have been described in the literature and they mostly resulted from widespread liver metastases that eventually involved ...

AIMS Immunological disturbances including innate immunity after a suspected viral infection are considered important to the pathogenesis of bile duct lesions in cases of biliary atresia (BA). In this study, we tried to evaluate whether natural killer (NK) cells and CX3CL1 (Fractalkine) and its receptor (CX3CR1) are involved in the bile duct injury. METHODS Using the section of BA (22 cases) a...

The production of bile is an essential function of the liver. It contains cholesterol, bile acids, pigments and electrolytes, and their concentration is modified when the bile transits through the biliary tract. The bile is produced by the hepatocytes and is secreted into the bile canaliculi. These canaliculi are delineated by the apical membrane of the hepatocytes and are connected to the netw...

Bile ducts from patients with PSC are enriched in neutrophils and biliary-resident CD8 + T cells differ composition liver tissue.

The patient was a 56-year-old woman who had experienced epigastralgia and dorsal pain several times over the last 20 years. She was admitted for a diagnosis of acute cholecystitis, and severe intra- and extrahepatic bile duct dilatation with inner air density was noted. No papilla of Vater was present in the descending duodenum, and 2 small holes were present in the pyloric ring. Bile excretion...