LABORATORY DATA biochemical markers metabolic defect chromosomal assignment chromosome X localization chromosome Xq localization chromosome Xq28 localization gene, structural-functional anomalies G6PD (G6PD1) glucose-6-phosphate dehydrogenase, gene chr.Xq28 gene analysis-DNA analysis myelo-erythropoietic disorders glucose-6-phosphate dehydrogenase deficiency haemolytic anaemia isolated hematopo...

Citation: Misiak B, Frydecka D and Rybakowski JK (2016) Editorial: Endophenotypes for Schizophrenia and Mood Disorders: Implications from Genetic, Biochemical, Cognitive, Behavioral, and Neuroimaging Studies. Front. Psychiatry 7:83. doi: 10.3389/fpsyt.2016.00083 Editorial: Endophenotypes for Schizophrenia and Mood disorders: implications from Genetic, Biochemical, Cognitive, Behavioral, and Neu...

conclusions in psychoactive substance dependents, serum routine biochemistry parameters can be used to predict the need for intensive monitoring and treatment programs. results there was a statistically significant difference in the gamma-glutamyl transferase (ggt), uric acid, creatinine, urea, albumin, aspartate aminotransferase (ast) medians between the dependent and control groups (p < 0.05)...

background  autistic spectrum disorder (asd) is a neurodevelopmental disorder. there is a large quantity of evidence which point towards a positive correlation between autism and mitochondrial disorders (md). in addition to that, several published reports, indicate that people with neurological disorders exhibit pathological signs of mitochondrial disorders and vice versa. screening for underly...

Metabolic disorders are a relatively uncommon, but important, cause of childhood seizures. Routinely searching for a metabolic disorder in epilepsy is usually unrewarding. Children and adolescents with epilepsy can be selected for appropriate biochemical investigation by considering the seizure type, age of onset, EEG appearance, family history, clinical findings and the results of brain imagin...

Using a single-molecule fluorescence approach, the time series of catalytic events of an enzymatic reaction can be monitored, yielding a sequence of fluorescent "on"- and "off"-states. An accurate on/off-assignment is complicated by the intrinsic and extrinsic noise in every single-molecule fluorescence experiment. Using simulated data, the performance of the most widely employed binning and th...