BACKGROUND At present, infrared (IR) imaging is used both as a non-invasive and a non-ionizing technology. Using an IR camera, it is possible to measure body surface temperature in order to detect tumors and malignant cells. Tumors have a high amount of vasculature and an enhanced metabolism rate, which may result in an increase in body surface temperature by several degrees above its normal le...

Abstract We investigate a quasilinear system consisting of the Westervelt equation from nonlinear acoustics and Pennes bioheat equation, subject to Dirichlet or Neumann boundary conditions. The concept maximal regularity type $$L_p$$ L p – $$L_q$$ q is ...

This paper presents a hybrid finite element model for describing quantitatively the thermal responses of skin tissue under laser irradiation. The model is based on the boundary integral-based finite element method and the Pennes bioheat transfer equation. In this study, temporal discretization of the bioheat system is first performed and leads to the well-known modified Helmholtz equation. A ra...

Theoretical analysis on the bioheat transfer process has been an extremely important issue in a wide variety of bioengineering situations such as cancer hyperthermia, burn injury evaluation, brain hypothermia, disease diagnostics, thermal comfort analysis, cryosurgery and cryopreservation etc. In this chapter, the theoretical strategies towards exactly solving the three-dimensional (3-D) biohea...

In this work, a method for estimating the space-dependent perfusion coefficient parameter in a 2D bioheat transfer model is presented. In the method, the bioheat transfer model is transformed into a time-dependent semidiscrete system of ordinary differential equations involving perfusion coefficient values as parameters, and the estimation problem is solved through a nonlinear least squares tec...

BACKGROUND Investigation of bioheat transfer problems requires the evaluation of temporal and spatial distributions of temperature. This class of problems has been traditionally addressed using the Pennes bioheat equation. Transport of heat by conduction, and by temperature-dependent, spatially heterogeneous blood perfusion is modeled here using a transport lattice approach. METHODS We repres...

To predict temperature distribution in a finite biological tissue simultaneously subjected to oscillatory surface and spatial heating, we apply a nonlinear one-dimensional temperature-dependent blood perfusion bioheat Pennes transfer equation. Going from works of Jens Lang et al. in IEEE Trans. on Biomedical Engineering (1999) pp. 1129–138 and Tzu-Ching et al. in Medical Engineering & Physics 2...

The finite difference time domain method is used to calculate the specific absorption rate (SAR) due to a butterfly surface coil in a realistic tissue model of the leg. The resulting temperature distribution and temperature changes are found using a finite difference solution to the bioheat transfer equation. Reasonable agreement is found between predicted temperature changes and those measured...

In non-invasive thermal diagnostics for the location of a tumor, accurate correlations between the thermal image on skin surface and interior human physiology are often desired, which require general solutions for the bioheat equation. In this paper we use sensitivity analysis in order to compute the shape derivative of the funtional that provides the minimum (the geometrical position of the tu...