نتایج جستجو برای: biological attributes
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The biologic mechanisms which result in alveolar bone loss have been well investigated but they are unique to each individual patient. Evidence based decision making (EBDM) is based on statistical and or epidemiological data generally gathered through systematic meta-reviews of randomized clinical trials. Personalized periodontal therapy, on the other hand is based a better understanding of hea...
Background Cellca is a recognized leader in cell line and upstream process development for large-scale protein production of biopharmaceuticals (e.g. antibodies) in mammalian cells and offers a unique platform technology which is characterized by high efficiency regarding productivity, scalability, and protein quality. As the market for therapeutic proteins is steadily growing, the need to opti...
The present article proposes the adoption of a community-defined, uniform, generic description of the core attributes of biological databases, BioDBCore. The goals of these attributes are to provide a general overview of the database landscape, to encourage consistency and interoperability between resources and to promote the use of semantic and syntactic standards. BioDBCore will make it easie...
In this paper we introduce a new method for extracting enriched biological functions from transcriptomic databases using an integrative bi-classification approach. The initial gene datasets are firstly represented as a formal context (objects × attributes), where objects are genes, and attributes are their expression profiles and complementary informations of different knowledge bases. After th...
Robust and scalable techniques for mining patterns or subgraphs in protein protein interaction (PPI) networks can help identify functionally relevant and coherent subnetworks. Recently, researchers have focused on integrating genes attributes with the protein-protein interaction networks for mining connected subnetworks whose genes are similar in a subset of attributes. However, most of the pro...
Introduction Increasing cow efficiency requires optimizing the ratio of output to input. Evaluating the market endpoint, resources, and management preferences is the first step in determining the attributes that are needed in the cow herd. The next step is identifying the biological attributes of the cow that fits your production system. Around the world the ecologies of grazing systems vary gr...
A biosimilar is a biological medicinal product that is comparable to a reference medicinal product in terms of quality, safety, and efficacy. SB4 was developed as a biosimilar to Enbrel® (etanercept) and was approved as Benepali®, the first biosimilar of etanercept licensed in the European Union (EU). The quality assessment of SB4 was performed in accordance with the ICH comparability guideline...
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