In this paper, we present a model that explains the prepatterning of lymphatic vessel morphology in collagen gels. This model is derived using the theory of two phase rubber material due to Flory and coworkers and it consists of two coupled fourth order partial differential equations describing the evolution of the collagen volume fraction, and the evolution of the proton concentration in a col...

A sensitive monitoring of biological analytes, such as biomolecules (protein, lipid, DNA and RNA), and biological cells (blood cell, virus and bacteria), is essential to assess and avoid risks for human health. Nanobiosensors, analytical devices that combine a biologically sensitive element with a nanostructured transducer, are being widely used for molecular detection of biomarkers associated ...

BRIEFING 1 2 <1032> Design and Development of Biological Assays. This General Chapter 3 Design and Development of Bioassays <1032> is one of an integrated group of new 4 General Chapters that provide guidance across several complementary bioassay topics. 5 The others include Biological Assay Validation <1033>; Analysis of Biological Assay 6 <1034>; and an as-yet unnumbered " roadmap " chapter t...