today hydrogels are considered as the materials that are able to play important role in drug delivery systems. to design an effective hydrogel applicable network, mathematical modeling has a critical role. a successful drug delivery device relies not only on intelligent network design but also on accurate prior mathematical modeling of drug release profiles. in this study, the modeling of the i...

Polyhydroxyalkanoates, or PHAs, belong to a class of biopolyesters where the biodegradable PHA polymer is accumulated by microorganisms as intracellular granules known carbonosomes. Microorganisms can accumulate using wide variety substrates under specific inorganic nutrient limiting conditions, with many carbon-containing coming from waste low-value sources. PHAs are universally thermoplastic,...

Polyhydroxyalkanoate (PHA) is a biopolyester/bioplastic that is produced by a variety of microorganisms to store carbon and increase reducing redox potential. Photosynthetic bacteria convert carbon dioxide into organic compounds using light energy and are known to accumulate PHA. We analyzed PHAs synthesized by 3 purple sulfur bacteria and 9 purple non-sulfur bacteria strains. These 12 purple b...

BACKGROUND Halophilic bacteria have shown their significance in industrial production of polyhydroxyalkanoates (PHA) and are gaining more attention for genetic engineering modification. Yet, little information on the genomics and PHA related genes from halophilic bacteria have been disclosed so far. RESULTS The draft genome of moderately halophilic bacterium, Halomonas sp. TD01, a strain of g...

Polyhydroxyalkanoates (PHA) have been produced by some bacteria as bioplastics for many years. Yet their commercialization is still on the way. A few issues are related to the difficulty of PHA commercialization: namely, high cost and instabilities on molecular weights (Mw) and structures, thus instability on thermo-mechanical properties. The high cost is the result of complicated bioprocessing...

This manuscript presents the synthesis and structural characterisation of novel biodegradable polymeric controlled-release systems of pesticides with potentially higher resistance to weather conditions in comparison to conventional forms of pesticides. Two methods for the preparation of pesticide-oligomer conjugates using the transesterification reaction were developed. The first method of obta...

The present study focuses on investigating the ability of haloarchaeal strain Natrialba swarupiae to synthesize polyhydroxyalkanoates. A homology model PHA synthase was validated and molecular docking studies were carried out.