Highly efficient and eco-friendly protocol for the synthesis of bis(3-indolyl)methanes by the electrophilic substitution reaction of indole with aldehydes catalyzed by poly(4-vinylpyridinium)hydrogen sulfate was described. Excellent yields, shorter reaction times, simple work-up procedure, avoiding hazardous organic solvents, and reusability of the catalyst are the most obvious advantages of th...

Aromatic carbonyl compounds in combination with B(C(6)F(5))(3) are able to activate H(2) heterolytically. The reactivity of the carbonyl-B(C(6)F(5))(3) adduct is initiated by its thermal dissociation into components. After H(2) addition, aromatic carbonyl compounds convert into aryl-substituted methanes or alcohols.

Optically active 1,2-bis(alkylmethylphosphino)ethanes and bis(alkylmethylphosphino)methanes are unique diphosphine ligands combining the simple molecular structure and P-stereogenic asymmetric environment. This work shows that these ligands exhibit excellent enantioselectivity in rhodium-catalyzed asymmetric hydrogenation of , -unsaturated phosphonic acid derivatives. The enantioselective hydro...

benzyltriphenylphosphonium bromide (btpb) has been applied as an efficient catalyst for the preparation of bis(indolyl)methanes (bims) via electrophilic substitution of indoles with aldehydes in the absence of solvent.

ammonium monovanadate (nh4vo3) has been devoted as an efficient, commercially available, eco-friendly and reusable catalyst for the synthesis of bis(indolyl)methanes (bims), oxindole derivatives and also michael adducts of indoles at 50 °c under solvent-free conditions. the reusability of this solid acid catalyst in addition with its selectivity has also been examined.

The high yield electrophilic substitution procedure for the synthesis of bis indolyl methanes at room temperature has been carried out effectively by using a novel metal supported organo catalyst. advantages this method include simple conditions, great yields, less work-up, an environmentally friendly process and reusable solid Several were synthesised confirmed IR, H1 13C NMR techniques. Catal...

A Pd-catalyzed cascade oxidation/sp(2) C-H bond acylation of azoarenes was developed in which readily available aryl methanes were used as the in situ generated acyl sources. This reaction provides a convenient access to ortho-acyl azoarenes under mild conditions.

Polymer supported dichlorophosphate (PEG-OPOCl(2)) is an efficient green catalyst for the electrophilic substitution reaction of indole with aromatic aldehydes, in neat condition, to afford an excellent yield of bis(indolyl) methanes with short reaction time, at room temperature. The synthesized compounds and their anti-cancer activity are evaluated.

An efficient procedure has been researched for the solvent-free synthesis of bis(indolyl)methanes via a one-pot reaction of indoles and aldehydes or ketones promoted by PEG1000-based dicationic acidic ionic liquid (PEG1000-DAIL). The catalyst PEG1000-DAIL could be reused seven times with excellent results. Furthermore, through this method, a highly chemoselective reaction of benzaldehyde and ac...