We investigated the toxicity of the fixed oil of Nigella sativa L seeds in mice and rats through determination of LD50 values and examination of possible biochemical, hematological and histopathological changes. The acute toxicity of Nigella sativa fixed oil was investigated in mice. LD50 values, obtained by single doses, orally and intraperitoneally administered in mice, were 28.8 ml/kg body w...

Nigella sativa, known as black seed, has analgesic, anti-inflammatory, antioxidant and anticancer effects. It has been shown to reduce the development of kidney failure when given prior to the use of nephrotoxic drugs particularly due to its antioxidant action. However, as far as the authors could ascertain, there is no human study in literature showing these effects. Here we present a case of ...

Because the need of increasing the medicinal plant production all over the world, its production became an ultimate goal to meet the great increase of population to avoid chemical therapy side effects on human health through utilization of the medical herbs. However, the use of the most suitable and recommended agricultural practices in growing such crops could provide the producers with higher...

Peptic ulcer disease (PUD) is a sore in the lining of stomach or duodenal mucosa. This study was aimed at evaluating antiulcer activity aqueous extract Nigella sativa (black seed) and its constitutents. The pharmacognostic properties dry seeds were determined. extracted using two methods digestion hydro-distillation. acute toxicity, phytochemical constituents evaluation performed on ethanol-ind...

OBJECTIVE The incidence and prevalence of kidney stone is increasing worldwide. After the first recurrence the risk of subsequent relapses is higher and the time period between relapses is shortened. Urinary stones can be severely painful and make a huge economic burden. The stone disease may increase the vulnerability of patients to other diseases such as renal failure. Medicinal herbs are ric...

Two field experiment were conducted to evaluate the effect of different fertilizer on seed yield and oil content two Black cumin species (Nigella sativa Nigella arvensis), first was at Qlyasan Agricultural Research Station, College Engineering Sciences, University Sulaimani, second Kanipanka Sulaimani Directorate, Ministry Agriculture Water Recourses during autumn season 2020-2021. The laid out...

The Nigella sativa L. popularly referred to as black seeds are widely used as a form of traditional nutrition and medicine. N. sativa seeds were used for the extraction of their oil by way of supercritical fluid extraction (SFE) and cold press (CP) to determine the physicochemical properties, antioxidant activity, and thermal behavior. The GC-MS results showed the primary constituents in the Ni...

BACKGROUND Limited evidence supports Nigella sativa's role as an effective complementary and alternative medicine and the anti-inflammatory effects of Nigella sativa on patients with allergic rhinitis. OBJECTIVE The aim of this study was to investigate the effect of topical application of Nigella sativa oil and oral acetaminophen on pain in the elderly with knee osteoarthritis residing in a p...

Acoustic trauma is a common reason for hearing loss. Different agents are used to prevent the harmful effect of acoustic trauma on hearing. The aim of this study was to evaluate the potential preventive effect of Nigella sativa (black cumin) oil in acoustic trauma. Our experimental study was conducted with 20 Sprague Downey female rats (mean age, 12 months; mean weight 250 g). All of the proced...

background: despite availability and administration of numerous antiepileptic drugs (aeds) nearly 15% of childhood epilepsy cases are resistant to treatment; in traditional medicine however nigella sativa l. (black seed) has been known for its anticonvulsant effects. materials and methods: in this double-blind clinical trial conducted on children with refractory epilepsy we administered the aqu...