CTX-M genes are the most prevalent ESBL globally, infiltrating nosocomial, community and environmental settings. Wild and domesticated animals may act as effective vectors for the dissemination of CTX-producing Enterobacteriaceae. This study aimed to contextualise blaCTX-M-14-positive, cephalosporin-resistant Enterobacteriaceae human infections and compared resistance and pathogenicity markers ...

Only the plasmid from the human E. coli isolate differed in RFLP fingerprint pattern from the other blaCTX-M-2-carrying plasmids. Southern blot hybridization with a blaCTX-M-2 probe revealed a .10 kb EcoRI fragment in the plasmids from the porcine and broiler E. coli isolates and from the Salmonella Virchow CODA-1 isolate. Two EcoRI fragments of 6 and 10 kb were found in the plasmid from the hu...

BACKGROUND A high rate of resistance to 3rd generation cephalosporins among Enterobacteriaceae isolates from Egypt has been previously reported. This study aims to characterize the resistance mechanism (s) to extended spectrum cephalosporins among resistant clinical isolates at a medical institute in Cairo, Egypt. METHODS Nonconsecutive Klebsiella pneumoniae (Kp), Enterobacter cloacae (ENT) a...

We characterized extended-spectrum beta-lactamases (ESBLs) and plasmid-mediated quinolone resistance (PMQR) in 32 Escherichia coli extended spectrum cephalosporin (ESC)-resistant clinical isolates from UK companion animals from several clinics. In addition, to investigate the possible dissemination of ESBL clinical isolates within a veterinary hospital, two ESBL-producing E. coli isolates from ...

BACKGROUND/AIM The aim of this study was to determine the prevalence of fecal carriage of extended-spectrum beta-lactamase (ESBL)-producing bacteria, enzyme types, and risk factors affecting colonization. MATERIALS AND METHODS A total of 576 stool samples from outpatients were examined between October 2012 and May 2013. Screening was done with selective EMB plates. ESBL were detected by doubl...

BACKGROUND Escherichia coli producing ESBL/AmpC enzymes are unwanted in animal production chains as they may pose a risk to human and animal health. Molecular characterization of plasmids and strains carrying genes that encode these enzymes is essential to understand their local and global spread. OBJECTIVES To investigate the diversity of genes, plasmids and strains in ESBL/AmpC-producing E....

Antimicrobial-resistant bacteria and resistance determinants are of great concern to human veterinary medicine worldwide. Extended-spectrum ?-lactamase (ESBL)-producing resistant broad-spectrum cephalosporins. ESBL-producing isolates, including those carrying blaCTX, blaPER, blaVEB, blaGES, have been reported from rivers in several countries.1 In a study performed 2018, using next-generation se...

Background: There is a growing concern on the impact of the presence of extended-spectrum β-lactamase (ESBL) producing Escherichia coli isolated from animals on public health. OBJECTIVES: The aim of this study was to investigate the presence of three classes of ESBL genes in E. coli isolates from sheep and broilers at a slaughter in Urmia region, Iran. METHODS: A total of 111 E. coli isolates w...

Sir, In Gram-negative bacteria, extended-spectrum b-lactamases (ESBLs) are widespread enzymes conferring resistance to most b-lactams, including third-generation cephalosporins but with the exception of carbapenems and cephamycins. In animals, the blaCTX-M-1 gene is one of the most frequently reported ESBL-encoding genes; in contrast, in humans the blaCTX-M-15 gene is highly prevalent. Plasmids...