Blood coagulation is an extremely complicated and dynamic physiological process. Monitoring of blood coagulation is essential to predict the risk of hemorrhage and thrombosis during cardiac surgical procedures. In this study, a high throughput microfluidic chip has been developed for the investigation of the blood coagulation process under temperature and hematocrit variations. Electrical imped...

Alterations of the coagulation potential of heparinized blood after using an extracorporeal circulation have been studied by means of a toluidine blue-calcium chloride reagent. This technique was originally used to detect the effect of activation by contact on the coagulation mechanism in heparinized blood. It has been shown that it also detects, in the presence of heparin, the clotpotentiating...

Human blood at physiological conditions is kept as fluid through precise system called homeostasis, if damage to the vessel, causing the system will be restored by vessel wall. Cases no regulation or homeostasis disorders, thrombosis (intravascular coagulation) or bleeding occur. In normal conditions, the secretion of vascular endothelial heparin-like and trmbomodulin molecules prevent blood co...