1.1. Purpose of pre-transfusion guidelines. Technical errors and/or inappropriate test systems or administrative errors may result in immediate and delayed haemolytic transfusion reactions. The purpose of these guidelines, which replace those previously published (BCSH, 1991a), is to define organizational, documentation and technical procedures undertaken in hospital or Regional Transfusion Cen...

Pre-transfusion testing is performed to ensure the normal survival of transfused red blood cell products i.e. to prevent hemolytic transfusion reaction via immune-mediated mechanism [1]. The serological part of pre-transfusion testing includes; ABO group and Rh (D) type, antibody screening and crossmatching [2]. Antibody screening is included to detect unexpected antibody and was first introduc...

1250 June 2013 W ORLD-WIDE, several hundred million operations are performed each year. A substantial fraction require blood transfusion, often with little forewarning. Because crossmatching and antibody screening takes time, it is conventional to either typeand-screen or crossmatch blood for patients likely to require transfusion. The clinical challenge is to predict who will require transfusi...

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