We describe a prototype system for preparing multiple fractions of blood components (plasma, washed erythrocytes, and hemolysates) by use of automated techniques. The procedure is based on centrifugal separation and sample transfer by induced pressure differentials in a blood-processing vessel (rotor) that has been designed to process 24 samples simultaneously. Erythrocytes are sedimented again...

Malaria is still a major problem in many parts of the world. Accurate diagnosis, crucial in disease control, currently relies on the microscopic detection of parasites in blood samples. This technique is invasive, increases risk of blood-borne disease transmission, and is uncomfortable for the patient. Non-invasive approaches to detect antibodies against malaria, malarial antigens, and malarial...

Penile blood gas can aid in the determination of the subtype of priapism to further guide treatment. A pH 7.25, PO2 30, and PCO2 60 indicate low-flow (ischemic) priapism, which needs to be treated immediately by administration of phenylephrine and draining of blood from the penis. High-flow priapism (1, 2) is usually self-limiting. The sequential samples were obtained to determine the effective...

Proof of principle has been shown for a rapid, quantitative, homogeneous immunoassay capable of analyzing whole-blood samples. The assay was performed with test cards and a small instrument designed for use at the point of care. The immunoassay has an immunological "front end" combined with a coagulation cascade chemistry "back end" and is made possible by combining two patented technologies: (...

T IS DIFFICULT to perform accurate fibrinogen assays on small samples of blood. A significant fraction of the plasma is lost when it is separated from the cells in 0.1or 0.2-mi. samples of blood and the plasma is diluted to a variable, usually undetermined, extent by the addition of anticoagulant. This can be minimized by using heparin dried in capillary tubes, but heparin interferes with subse...