The editorial by Forconi and Gori [1] challenges a cornerstone of cardiovascular physiology in questioning the interpretation of Hagen–Poiseuille’s law for viscous liquid flow in tubes in making the link between the fluid mechanical properties of blood and how these translate into physiological effects, which ultimately set peripheral vascular resistance, blood pressure and cardiac output. Appl...

We investigated 100 consecutive cerebral ischemia patients for hemorheological alterations. We measured whole and adjusted blood viscosity at 75 and 1,500 sec-1, plasma viscosity, red blood cell aggregation by the zeta sedimentation ratio, and red blood cell deformability using the centrifugal deformability technique. Patients were studied within 72 hours of the acute ischemic event, and 66 wer...

An excessive elevation in body temperature is known to decrease exercise performance. The physiological mechanisms involved with hyperthermia-induced fatigue include central nervous system dysfunction and cardiovascular instability. Conversely, a moderate increase in body temperature has been shown to actually improve exercise performance. Asmussen and Boje reported that sprint performance impr...

Blood viscosity and its contributory factors--namely, plasma viscosity, fibrinogen concentration, packed cell volume, red-cell deformability, and platelet count--were measured in 20 asymptomatic patients after splenectomy and compared with those in controls. Whole-blood viscosity was significantly increased after splenectomy and was associated with increased platelet count and, more importantly...

Lipid profile, haematocrit, fibrinogen, and blood viscosity were studied in 26 healthy volunteers (15 premenopausal, 11 post menopausal). Menopausal women had significantly higher total cholesterol, fibrinogen, hematocrit and blood viscosity levels as compared to premenopausal women. Also, triglyceride, LDL-cholesterol and HDL-cholesterol levels were higher in menopausal women, but the differen...

During the coagulation process, blood changes from a liquid to a solid gel phase. These changes are reflected by changes in blood viscosity; however, blood viscosity at different shear rates (SR) has not been previously explored during the coagulation process. In this study, we investigated the viscosity changes of whole blood in 10 subjects with a normal coagulation profile, using a cone-on-pl...

Disturbances of the microcirculation and abnormal hemorheological properties are important factors that play an important role in disseminated intravascular coagulation (DIC) and result in organ dysfunction or failure. In the present study, we established an animal model of DIC using intravenous Dextran 500 in rats, and used exogenous normal lymph corresponding to 1/15 of whole blood volume for...

Background—Several hemostatic and rheological factors have been associated with incident cardiovascular events. However, there have been no reports on the relationship of rheological factors with early atherosclerosis and very few on hemostatic factors. We therefore studied the relationship between these factors and carotid intima-media thickness (IMT). Methods and Results—The Edinburgh Artery ...

BACKGROUND Several hemostatic and rheological factors have been associated with incident cardiovascular events. However, there have been no reports on the relationship of rheological factors with early atherosclerosis and very few on hemostatic factors. We therefore studied the relationship between these factors and carotid intima-media thickness (IMT). METHODS AND RESULTS The Edinburgh Arter...

Previously, we have reported that rye significantly increased both viscosity and Clostridium perfringens proliferation when compared with corn in an in vitro digestive model. Two independent trials were conducted to evaluate the effect of rye as a source of energy on bacterial translocation, intestinal viscosity, gut microbiota composition, and bone mineralization, when compared with corn in tu...