Babesia bovis is a tick-borne intraerythocytic protozoan responsible for acute disease in cattle which can be controlled by vaccination with attenuated B. bovis strains. Emerging B. bovis transfection technologies may increase the usefulness of these live vaccines. One use of transfected B. bovis parasites may be as a vaccine delivery platform. Previous transfection methods for B. bovis were li...

Adenoviruses are used extensively to deliver genes into mammalian cells, particularly where there is a requirement for high-level expression of transgene products in cultured cells, or for use as recombinant viral vaccines or in gene therapy. In spite of their usefulness, the construction of adenoviral vectors (AdV) is a cumbersome and lengthy process that is not readily amenable to the generat...

background: various adverse effects of homologous blood transfusion detected particularly in open heart surgery, in which it is frequently used, lead researchers to study on autologous blood use and to evaluate the patient’s blood better. due to the complications of homologous blood transfusion, development of techniques that utilize less transfusion has become inevitable. we aimed to evaluate ...

background: colorectal cancer is the third cause of cancer death in western countries. age, inadequate diet, obesity, inactivity and genetic changes are some of the risk factors of colorectal cancer. correlation of genetic diversity in homologous recombination repair system with cancer was evaluated in many recent studies. this study was done to investigate the correlation of t241m polymorphism...

background and aim the most common complication of renal transplantation is allograft dysfunction, which in some cases leads to graft loss. the role of graft nephrectomy in the management of transplant failure is controversial. the procedure remains associated with a significant morbidity and also mortality. our main purpose was the comparison between clinical and pathological diagnosis of graf...

Tick vaccines have been available for more than 20 years. They are useful and effective control agents when used properly. However, no new products have emerged since the Bm86-based Gavac vaccine was commercialized. Acaricide resistance is a problem with no abatement in sight and anti-tick vaccines are likely to be relied upon even more in the coming years. As human medicine and plant agricultu...