نتایج جستجو برای: bn20
تعداد نتایج: 47 فیلتر نتایج به سال:
Glioblastoma is the most common malignant brain tumor in adults. Baseline health-related quality of life (HRQoL) is a major subject of concern for these patients. We aimed to assess the independent prognostic value of HRQoL in unresectable glioblastoma (UGB) patients for death risk stratification. One hundred and thirty-four patients with UGB were enrolled from the TEMAVIR trial. HRQoL was eval...
AIM Both brain tumors and their treatments have a major negative impact on the quality of life (QoL). EORTC BN20 and Functional Assessment of Cancer Therapy-Brain (FACT-BR) are the most commonly used tools to assess QoL. The FACT-BR is a 23-item questionnaire, especially about the psychosocial aspects of QoL. This paper describes the challenges we faced during the process of translation and val...
INTRODUCTION Patients suffering from brain tumours often experience a wide range of cognitive impairments that impair their ability to report on their quality of life and symptom burden. The use of proxy ratings by significant others may be a promising alternative to gain information for medical decision making or research purposes, if self-ratings are not obtainable. Our study investigated the...
Abstract Based on the EF-14 trial, Tumor Treating Fields (TTFields) therapy is recommended in treatment guidelines for newly diagnosed glioblastoma (GBM). However, real-world data are limited. The non-interventional TIGER study (NCT03258021) will give insight into patients’ decision, TTFields duration and usage, quality of life, overall survival, adverse events (AEs) setting. Subsequently, we h...
BACKGROUND The role of reoperation for recurrent glioblastoma (GBM) remains unclear. Prospective studies are lacking. Here, we studied the association of clinical outcome with extent of resection upon surgery for recurrent GBM in the patient cohort of DIRECTOR, a prospective randomized multicenter trial comparing 2 dose-intensified temozolomide regimens at recurrence of GBM. METHODS We analyz...
Abstract Background Transabdominal ultrasound scan (USS) is recommended for surveillance of gallbladder polyps (GBP), this to stratify risk premalignant potential. European Society Gastrointestinal and Abdominal Radiology make recommendations based on increases as small 2mm during sequential USS surveillance. Our aim determine the accuracy in diagnosis measurement GBP. Methods Measurement data ...
Background In the EORTC 1410/INTELLANCE 2 randomised, phase II study (NCT02343406), with antibody–drug conjugate depatuxizumab mafodotin (Depatux-M, ABT-414) in patients recurrent EGFR-amplified glioblastoma, primary end-point (overall survival) was not met, and drug had ocular dose-limiting toxicity. This reports results from prespecified health-related quality of life (HRQoL) neurological det...
BACKGROUND Surgical management of suspected LGG remains controversial. A key factor when deciding a surgical strategy is often the tumors' perceived relationship to eloquent brain regions OBJECTIVE To study the association between tumor location, survival and long-term health related quality of life (HRQL) in patients with supratentorial low-grade gliomas (LGG). METHODS Adults (≥18 years) o...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید