Enoxaparin sodium is a low-molecular-weight heparin. It is not clear whether the risk of development of osteoporosis after administration of low-molecular-weight heparins is lower than after administration of standard heparin. The aim of the present study was to investigate the effects of enoxaparin on histomorphometric parameters of bones in female Wistar rats (13-15 weeks old at the beginning...

Raloxifene, a selective estrogen receptor modulator, is used for prevention and treatment of osteoporosis in postmenopausal women. Raloxifene use in male subjects is increasingly considered and a few clinical studies of its effect on bone turnover have already been performed. The aim of the present study was to investigate the effects of raloxifene on the skeletal system of healthy mature male ...

BACKGROUND This study evaluates the clinical, radiological, histological, and histomorphometric aspects of a fully synthetic biphasic calcium phosphate (BCP) (60% hydroxyapatite and 40% ß-tricalcium phosphate), used in a human maxillary sinus floor elevation (MSFE) procedure with 9- and 12-month healing time. METHODS A unilateral MSFE procedure, using 100% BCP, was performed in two series of ...

PURPOSE Surgery of irradiated tissue has an increased complication rate because of the development of hypovascular, hypocellular, and hypoxic tissue. This study was undertaken to perform histopathologic and histomorphometric analyses of irradiation tissue injury in bone and the surrounding soft tissues. MATERIAL AND METHODS The histopathologic findings of 40 human mandibular bones and the sur...

Tetracyclines are considered potential medication for the treatment of osteoporosis. The aim of the present study was to investigate the effects of doxycycline on development of unfavorable changes in bone histomorphometric parameters induced by bilateral ovariectomy in rats. Doxycycline at a dose of 20 mg/kg po daily was administered for 28 days to bilaterally ovariectomized and sham-operated ...

Bone specimens were obtained from four different sites in the ilium of necropsy cases using a Jamshidi 8G trephine needle. Undecalcified histological sections were prepared and two structural histomorphometric parameters were estimated. Estimates of the percentage of trabecular bone volume (%TBV) deviated systematically, with variation of the biopsy site around the usual location, increasing in...

PURPOSE This study evaluated the stability and histologic proof of osseoincorporation of Trabecular Metal (TM) dental implants, which feature a tantalum-based porous midsection. MATERIALS AND METHODS A total of 48 TM implants (test group) and Tapered Screw-Vent implants (control group) were immediately placed bilaterally into mandibular extraction sockets in dogs. Resonance frequency analysis...

Aims: The aim of the current study is to evaluate effect Aloe Vera gel on healing process surgically made maxillary alveolar bone defects and new tissue formation in rabbits. Materials Methods: Twenty albino rabbits were randomly chosen conduct study, all selected inhabited under same circumstances involving ventilation, temperature, diet. Each rabbit received anesthetic solution separately und...

OBJECTIVE To investigate in detail the mechanical and structural characteristics of cancellous bone from the femoral distal epiphysis of normal and ovariectomized rats, and to provide reference values in order to improve experimental research on osteoporosis by characterising an alternative and complementary anatomic site. METHODS 40 female Sprague-Dawley rats (10 months old) were randomly di...