background: bone marrow has recently been recognized as a novel source of stem cells for the treatment of wide range of diseases. a number of studies on murine bone marrow have shown a homogenous population of rare stage-specific embryonic antigen 1 (ssea-1) positive cells that express markers of pluripotent stem cells. this study focuses on ssea-1 positive cells isolated from murine bone marro...

Stem cells are undifferentiated biological cells that can differentiate into specialized cells and can divide (through mitosis) to produce more stem cells. They are found in multicellular organisms. In mammals, there are two broad types of stem cells: embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and adult stem cells, which are found in various tissues. In ad...

objective(s): nowadays much effort is being invested in order to diagnose the mechanisms involved in neural differentiation. by clarifying this, making desired neural cells in vitro and applying them into diverse neurological disorders suffered from neural cell malfunctions could be a feasible choice. thus, the present study assessed the capability of fetal brain extract (fbe) to induce rat bon...

objectives: this study investigated the possible synergistic effect of simultaneous treatment of bone morphogenic protein (bmp)-4 as a chemical stimulator and static magnetic field (smf) as a physical stimulator on viability percent and proliferation rate in rat bone marrow stem cells. methods: passage 5 cells were trypsinized, and a cell suspension prepared after which the cells were counted ...

abstractbackground: fetal bovine serum (fbs) is widely used in cell culture laboratories,risk of zoonotic infections and allergic side effects create obstacles for its use inclinical trials. therefore, an alternative supplement with proper inherent growthpromotingactivities is demanded.objective: to find fbs substitute, we tested human umbilical cord blood serum(hucs) for proliferation of human...

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experimental and clinical studies have shown that intracoronary transplantation of autologous bone marrow mesenchymal stem cells (bmscs) has resulted in regenerated infarcted myocardium and improved left ventricular (lv) function.the aim of this pilot study was to assess the benefical effectsof intracoronary transplantation of bmsc in patients with oldmyocardial infarction (omi). autologous bms...

Stem cells are emerging as an attractive option because of their intrinsic ability vectors for drug delivery to diseased tissues. The term stem or was first introduced by a Russian histologist, Alexander Maksimov (1874-1928). purpose this study is describe the research and development cell applications stroke. This literature (review article) regarding (stem cells) in stroke which has been disc...