نتایج جستجو برای: bone morphogenetic protein 2

تعداد نتایج: 3672045  

Journal: :Journal of Biological Chemistry 2000

Journal: :The Journal of biological chemistry 2006
Eun-Joo Jeon Kwang-Youl Lee Nam-Sook Choi Mi-Hye Lee Hyun-Nam Kim Yun-Hye Jin Hyun-Mo Ryoo Je-Yong Choi Minoru Yoshida Norikazu Nishino Byung-Chul Oh Kyeong-Sook Lee Yong Hee Lee Suk-Chul Bae

Runx2/Cbfa1/Pebp2aA is a global regulator of osteogenesis and is crucial for regulating the expression of bone-specific genes. Runx2 is a major target of the bone morphogenetic protein (BMP) pathway. Genetic analysis has revealed that Runx2 is degraded through a Smurf-mediated ubiquitination pathway, and its activity is inhibited by HDAC4. Here, we demonstrate the molecular link between Smurf, ...

Journal: :International journal of clinical and experimental medicine 2015
Guo-Zhu Hou Feng Xu Wen-Ju Li Xiao-Meng Zhu Xing-Hua Song Yu-Lin Zhan

BACKGROUND It has been studied that the distribution of bone morphogenetic protein 2 is regular under bone defect situation. OBJECTIVE To observe the expression of bone morphogenetic protein 2 in rabbit radial defect site with different lengths. METHODS Forty-eight New Zealand rabbits were divided into two groups randomly. 0.5 cm bone defect and 3.0 cm bone defect were made by wire saw at t...

2012
Martin Waselau Mimmi Patrikoski Miia Juntunen Kasperi Kujala Minna Kääriäinen Hannu Kuokkanen George K Sándor Outi Vapaavuori Riitta Suuronen Bettina Mannerström Brigitte von Rechenberg Susanna Miettinen

The effects of bioactive glass S53P4 or beta-tricalcium phosphate; and bone morphogenetic proteins bone morphogenetic protein-2, bone morphogenetic protein-7, or bone morphogenetic protein-2 + 7 on osteogenic differentiation of human adipose stem cells were compared in control medium, osteogenic medium, and bone morphogenetic protein-supplemented osteogenic medium to assess suitability for bone...

Journal: :medical journal of islamic republic of iran 0
achmad fauzi kamal department of orthopaedic and traumatology, ciptomangunkusumo hospital, faculty of medicine, universitas indonesia, jakarta, indonesia. ismail hadisoebroto dilogo department of orthopaedic and traumatology, ciptomangunkusumo hospital, faculty of medicine, universitas indonesia, jakarta, indonesia. errol untung hutagalung department of orthopaedic and traumatology, ciptomangunkusumo hospital, faculty of medicine, universitas indonesia, jakarta, indonesia. diah iskandriati primate research center, bogor agricultural university, bogor, indonesia. r. susworo department of radiotherapy, ciptomangunkusumo hospital, faculty of medicine, universitas indonesia, jakarta, indonesia. nurjati chaerani siregar department of anatomical pathology, ciptomangunkusumo hospital, faculty of medicine, universitas indonesia, jakarta, indonesia.

background :delayed ::::union::::, non::::union::::, and mechanical failure is still problems encountered in limb salvage surgery (lss) using extracorporeal irradiation (eci). this study aimed to determine whether bone marrow mesenchymal stem cells (msc) and recombinant human bone morphogenetic protein-2 (rhbmp-2) improve host-graft ::::union:::: after osteotomy and also increase its mechanical...

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