In this 2022 Update of Version 2020 the VI Consensus Brazilian Society Bone Marrow Transplantation (SBTMO) for Graft-versus-Host-Disease (GVHD), we seek to provide evidence-based guidance on all novel and clinically relevant advancements in both prophylaxis therapy Graft-versus-Host Disease those who delve into field Hematopoietic Stem Cell Transplantation.

Hematopoietic stem/progenitor cells (HSPCs) which give rise to different blood cell types are present within the bone marrow microenvironment, especially in flat bones such as skull, vertebrae, pelvis and chest. Interacting factors such as stromal derived factor-1/CXCR4, very late antigen-4/vascular cell adhesion molecule-1, Lymphocyte function-associated antigen-1/ intercellular adhesion molec...

some of the genotypes of cytokines are associated with acute graft versus host disease after bone marrow transplantation. the purpose of the present investigation was to find out the possible association between transforming growth factor beta-1 (tgf-β1) codon 25 polymorphism (rs:1800471) and acute graft versus host disease (agvhd) after bone marrow transplantation from the sibling with the sim...

Organ transplantation is the gold standard therapy for several end-stage diseases. Bone loss is a common complication that occurs in transplant recipients. Osteoporosis and fragility fractures are serious complication, mainly in the first year post transplantation. Many factors contribute to the pathogenesis of bone disease following organ transplantation. This review address the mechanisms of ...

OBJECTIVE Bone Marrow Transplantation is considered one of the main procedures used in the treatment of both malignant and non-malignant diseases. Psychological factors after Bone Marrow Transplantation have an important role in the survival of the patients undergoing this procedure. METHOD In the present study, some parameters including depression, anxiety and cognition were assessed during ...

This summary is intended to update the Brazilian Society of Bone Marrow Transplantation and Cellular Therapy (SBTMO) 2020/1 consensus on HSCT for Acute Myeloid leukemia (AML).

Bone marrow transplant recipients may be at increased risk of osteoporosis. In a cross-sectional study we therefore measured two biochemical markers of bone turnover, bone alkaline phosphatase and the C-terminal propeptide of type I procollagen, in 22 serum samples from 9 patients before allogeneic bone marrow transplantation and 85 serum samples from 14 patients after allogeneic bone marrow tr...

mineral density changes within six months of renal transplantation. increased bone turnover and low bone density in long-term survivors to kidney transplantation. Posttransplant bone disease: evidence for a high bone resorption state. mineral density in kidney transplant recipients and patients on hemodialysis: a comparison with healthy individuals. Comparison of alendronate and pamidronate on ...