Essential amino acids (EAAs) are potent stimulators of mechanistic target of rapamycin complex 1 (mTORC1) signaling and muscle protein synthesis. However, regulators upstream of mTORC1 that are responsive to EAA availability are not well described, especially in human skeletal muscle. The purpose of this study was to determine changes in leucyl-tRNA synthetase (LARS/LARS) and Ras-related GTP bi...

A the Transport Area Open Meeting at IETF 70, area directors Magnus Westerlund and Lars Eggert noted that their queues are empty and that several Transport Area working groups are nearing completion. It may therefore be an opportune time to step back and consider possible directions for new projects in the Transport Area. !is article summarises some of the ideas presented and discussed at that ...

Slotting allowances are fees paid by manufacturers to get access to retailers’ shelf space. Both in the USA and Europe, the use of slotting allowances has attracted attention in the general press as well as among policy makers and economists. One school of thought claims that slotting allowances are efficiency enhancing, while another school of thought maintains that slotting allowances are use...

The purpose of this study was to assess the outcomes of posterior cruciate ligament (PCL) reconstruction using the Ligament Augmentation and Reconstruction System (LARS) (JK Orthomedic Ltd, Dollard-des-Ormeaux, Quebec, Canada) artificial ligament. Compared with older artificial ligaments, the LARS, which has been used in Europe for 15 years, is more resistant to wear and tear, has satisfactory ...

Modern processor architectures suffer from an ever increasing gap between processor and memory performance. The current memory-register model attempts to hide this gap by a system of cache memory. Line Associative Registers(LARs) are proposed as a new system to avoid the memory gap by pre-fetching and associative updating of both instructions and data. This thesis presents a fully LAR-based arc...

Permission is granted to quote short excerpts and to reproduce figures and tables from this report, provided that the source of such material is fully acknowledged. Abstract. This paper focuses on the characteristics and performance of an eye-safe laser range scanner (LARS) with short-and medium-range 3-D sensing capabilities for space applications. This versatile LARS is a precision measuremen...

The aims of this study were to analyze the preliminary clinical outcome of limb salvage using Ligament Advanced Reinforcement System (LARS). It is hypothesized that LARS ligament is a safe and effective choice to enhance prosthetic reconstructions, providing good muscles reattachment and improving joint stability. From March 2009 to March 2010, 7 patients received megaprosthesis reconstruction ...

BACKGROUND “Ankle sprain” is a common injury, and although most patients recover with non-operative treatment, more than 20% of patients may develop chronic instability. Numerous surgical techniques have been described for these patients. “Anatomic” procedures, such as the modified Brostrom-Gould procedure (MBG), are generally regarded as the treatment of choice. However, there is little high q...

Damage to knee articular ligaments causes important functional problems and adversely affects particularly the stability of the knee joint. Several methods were developed in order to repair damage to the anterior cruciate ligament (ACL), which employ autografts, allografts, as well as synthetic ligaments. One such synthetic scaffold, the ligament advanced reinforcement system (LARS) synthetic l...

CONTEXT Gastroesophageal reflux disease (GERD) is a chronic, relapsing disease with symptoms that have negative effects on daily life. Two treatment options are long-term medication or surgery. OBJECTIVE To evaluate optimized esomeprazole therapy vs standardized laparoscopic antireflux surgery (LARS) in patients with GERD. DESIGN, SETTING, AND PARTICIPANTS The LOTUS trial, a 5-year explorat...