In eukaryotic cells, the DNA material is densely packed inside the nucleus in the form of a DNA-protein complex structure called chromatin. Since the actual conformation of the chromatin fiber defines the possible regulatory interactions between genes and their regulatory elements, it is very important to understand the mechanisms governing folding of chromatin. In this paper, we show that supe...

In this study, the boundary element method is formulated to evaluate hydrodynamic characteristics of bodies including free surface effect. The method is based on two equations, the perturbation potential boundary integral and the pressure Kutta condition, which are solved simultaneously. The method uses isoparametric elements for both quantity and geometric on the boundary. The method is first ...

The parasegment-specific expression of the three Drosophila Bithorax complex homeotic genes is orchestrated by nine functionally autonomous regulatory domains. Functional autonomy depends upon special elements called boundaries or insulators that are located between each domain. The boundaries ensure the independent activity of each domain by blocking adventitious interactions with initiators, ...

We present a numerical method, based on a coupling of finite elements and boundary elements, to solve a fluid–solid interaction problem posed in the plane. The boundary unknowns involved in our formulation are approximated by a spectral method. We provide error estimates for the Galerkin method and present numerical results that illustrate the accuracy of our scheme.

We present a new Boundary Discontinuous Petrov-Galerkin (BDPG) method for Computational Fluid Dynamics (CFD) simulations. The method represents a modification of the standard Hybrid Discontinuous Galerkin (HDG) scheme, and uses locally-computed optimal test functions to achieve enhanced accuracy along the domain boundaries. This leads to improved accuracy in relevant boundary outputs such as li...

In this paper, vibration analysis of multiple-stepped Bernoulli-Euler and Timoshenko beams carrying point masses is presented analytically for various boundary conditions. Each attached element is considered to have both translational and rotational inertias. The method of solution is “transfer matrix method” which is based on the changes in the vibration modes at the vicinity of any discontinu...