Thirty colostrum-deprived calves from leukemia-free herds were foster nursed for 10 weeks on cows infected with bovine C-type virus (BLV) from multiple-case herds or on cows from leukemia-free herds. After weaning, the calves were raised in continuous contact with BLV-infected animals of approximately the same ages. Sera collected at 6 to 18 and 43 to 48 months of age were examined for the pres...

Direct evidence that Escherichia coli Shiga toxin (Stx) acts against bovine leukemia virus (BLV)-expressing cells was obtained. The active A subunit of Stx type 1 (StxA1) targeted a selected population of permeable cells expressing BLV and inhibited BLV replication in a culture of bovine peripheral blood mononuclear cells. Cells were cultured with and without StxA1, and at various times cells e...

Of tumor diseases in the global animal husbandry industry, greatest danger is bovine leukemia. Since last century, this neoplastic disease has remained relevant for veterinary medicine and, addition, more and questions arise concerning potential threat of Bovine leukemia virus (BLV) humans. The problem being discussed (G.Yu. Kosovskiy et al., 2016) which additionally stimulates both fundamental...

INTRODUCTION Bovine immunodeficiency virus (BIV) and bovine leukemia virus (BLV) have worldwide distributions, but their prevalences in Iran are unknown. We investigated the presence of infections in Iranian Holstein cattle and determined changes in hematological values for infected animals. METHODOLOGY Nested PCR was used on blood samples from 143 animals Holstein cattle to detect proviral B...

Bovine papillomavirus (BPV) DNA sequences were detected in different tissues, in addition to epithelium. Cytogenetic abnormalities were observed in blood lymphocytes. The presence of more than one virus in a single tissue is a difficult aspect to evaluate, especially when the DNA sequences are detected in tissues that are not specifically targeted by the virus. BPV and bovine leukemia virus (BL...

The inhibitory receptor programmed death-1 (PD-1) and its ligand, programmed death-ligand 1 (PD-L1) are involved in immune evasion mechanisms for several pathogens causing chronic infections. Blockade of the PD-1/PD-L1 pathway restores anti-virus immune responses, with concomitant reduction in viral load. In a previous report, we showed that, in bovine leukemia virus (BLV) infection, the expres...

The aim of the research is use serological and molecular genetic methods for detecting virus-infected cattle leukemia, as well determining significance PCR in identifying BLV infected calves system antiepizootic health measures. developed technique early diagnosis leukemia made it possible to accelerate process recovery disadvantaged farms Belgorod region by increasing frequency studies from 6 ...

Bovine leukemia virus (BLV) is an oncogenic deltaretrovirus that infects cattle worldwide. In Uruguay, it estimated more than 70% of dairy are infected, causing serious economic losses due to decreased milk production, increased calving interval, and livestock lymphosarcoma. Several attempts develop vaccine candidates activate protective immune responses against BLV were performed, but up date,...

Background: Bovine Leukemia Virus (BLV) is known by infections in bovine cattle and produce, in 30% of infected animals, persistent lymphocytosis significantly impacts the beef industry. It has been proposed that this virus could be transmitted to humans and be present in cases of breast cancer. Aim: to determine the presence of 380 bp of gag gene segment of BLV in paraffin-embedded breast tiss...

Abstract Background Subclinical infection with bovine leukemia virus (BLV) in cows can cause economic losses milk and meat production many countries, as BLV-related negative effects. The volatile fatty acids (VFAs) microbiota present the digestive tracts of contribute to cow health. Here, we exploratorily investigated VFAs rumen gut respect subclinical BLV using housed at a single farm. Results...