نتایج جستجو برای: brain hypoxia
تعداد نتایج: 522475 فیلتر نتایج به سال:
Abstract Brain hypoxia can occur after non-traumatic subarachnoid hemorrhage (SAH), even when levels of intracranial pressure (ICP) remain normal. tissue oxygenation (PbtO 2 ) be measured as a part neurological multimodal neuromonitoring. Low PbtO has been associated with poor neurologic recovery. There is scarce data on the impact guided-therapy patients’ outcome. This single-center cohort stu...
Sustained and diel-cycling hypoxia frequently occurs in high-latitude environments; however, fish's biochemical, physiological, histological responses to these two conditions remain unknown. Current hypotheses posit that the heart brain of fish from high latitudes are integral their tolerance exhibit different response mechanisms cope with sustained hypoxic conditions. To test this, we acclimat...
how to cite this article: wilson md. animal models of cerebral palsy: hypoxic brain injury in the newborn. iran j child neurol. spring 2015; 9(2):9-16. abstract objective hypoxic insults are implicated in the spectrum of fetal disorders, including cerebral palsy (cp). in view of the major contribution of intrapartum risk factors and prematurity to subsequent neurological morbidity and mortality...
The present study identifies several factors that govern brain pathologic response to marked hypoxia. None of 13 cats exposed to 25 minutes of marked hypoxia (FiO2 = 3.4%; PaO2 = 17 +/- 3 mm Hg, S.D.) that maintained mean arterial blood pressure (MABP) greater than 65 mm Hg were brain injured after reoxygenation and long term survival. In contrast, 12 of 13 exposed to the same hypoxia but that ...
Tyrosine hydroxylase, a hypoxia-regulated gene, may be involved in tissue adaptation to hypoxia. Intermittent hypoxia, a characteristic feature of sleep apnea, leads to significant memory deficits, as well as to cortex and hippocampal apoptosis that are absent after sustained hypoxia. To examine the hypothesis that sustained and intermittent hypoxia induce different catecholaminergic responses,...
BACKGROUND AND PURPOSE Hypoxia and hemodilution both reduce arterial oxygen content (CaO(2)) and increase cerebral blood flow (CBF), but the mechanisms by which hemodilution increases CBF are largely unknown. ATP-sensitive potassium (K(ATP)) channels are activated by intravascular hypoxia, and contribute to hypoxia-mediated cerebrovasodilatation. Although CaO(2) can be reduced to equal levels b...
Relevance . Ethylmethylhydroxypyridine succinate (EMHPS) is a reference domestic drug with pronounced antioxidant and antihypoxic activity. P-Glycoprotein (Pgp) an ATP-dependent transport protein localized in tissue barriers protecting cells organs from the effects of xenobiotics. Being expressed blood-brain barrier (BBB), Pgp limits penetration drugs toxic substances into brain tissue. Aim – t...
While extensive studies report that neonatal hypoxia-ischemia (HI) induces long-term cognitive impairment via inflammatory responses in the brain, little is known about the role of early peripheral inflammation response in HI injury. Here we used a neonatal hypoxia rodent model by subjecting postnatal day 0 (P0d) rat pups to systemic hypoxia (3.5 h), a condition that is commonly seen in clinic ...
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