introduction: the adaptive neuro-fuzzy inference system (anfis) is a soft computing model based on neural network precision and fuzzy decision-making advantages, which can highly facilitate diagnostic modeling. in this study we used this model in breast cancer detection. methodology: a set of 1,508 records on cancerous and non-cancerous participant’s risk factors was used.  first, the risk fact...

conclusions expression of armc3 in tumor samples and normal adjacent tissue is very important. the expression of this gene in tumor-adjacent tissue may be associated with the stage of cancer; it may be that these tissues are affected by epigenetic and oncogenic changes of breast cancer. accordingly, aberrant expression of armc3 in tumor samples may be an attractive candidate for use as a tumor ...

background: idiopathic granulomatous mastitis (igm) is a rare benign breast disease, which can mimic breast cancer. as the managements of igm and breast cancer are entirely different and the initial clinical manifestations are similar in several cases, it is very important to differentiate them. case presentation: we reported a 48-year-old female patient with igm and breast cancer. she was refe...

background: potential association of leptin (lep) gene polymorphisms has been suggested in the processes leading to breast cancer initiation and progression. we investigated whether genetic variations in the lep -2548g/a gene are associated with risk of breast cancer. methods: this case-control study consisted of 100 breast cancer cases and 100 control subjects without breast cancer that matche...

mri of the breast has evolved as a non-invasive imaging modality and is ideally suited for several indications e.g. pre-operative staging and screening in women at increased risk for breast cancer. the widespread use opens also the discussion on over-diagnosis if only 20 - 30 out of 100 mri - guided breast biopsies lead to the diagnosis of breast cancer. thus mri based strategies are needed to ...

Background: Breast cancer incidence has increased rapidly inKuwait, but there haven’t been any studies investigating the recognized risk factors of breast cancer inKuwait. The aim of the study was to investigate breast cancer risk factors among women inKuwait. Methods: A case-control study was conducted in Kuwait from May 2003 to March 2004 using a questionnaire including socio-demographic data...

Background: Prediction of breast cancer risk and identifying women who are at high risk of breast cancer, would be a great help for planning and conducting screening programs. The aim of this study was to estimate the 5-year breast cancer risk among women in Isfahan. Methods: This cross-sectional study was conducted on 9674 women aged 35-69 years who referred to the Breast Cancer Screening Cen...

abstract background: the increase in breast cancer incidence has enhanced attention towards breast cancer risk. the aim of this study was to determine the risk of breast cancer and risk perception of women, factors that affect risk perception, and to determine differences between absolute risk and the perception of risk. methods: this cross-sectional study was carried out among 346 women whose ...

background: cancer/testis antigens (ctas) are members of a group of proteins which are normally expressed in testis germ cells and to a lesser extent in the ovaries. because of recent reports about their aberrant and specific expression in some tumoral tissues, they may play a role as new candidates for targeted therapy. therefore, the study of the expression pattern of these biomarkers and its...

background: breast cancer is the most incident cancer and the fifth cause of death due to malignancies among iranian women. a strong breast cancer patients' sense of meaning and purpose in life appears to decrease anxiety in their life. the present study has investigated the effectiveness of group logotherapy on the reduction of anxiety in women with breast cancer. methods: the research was qua...