نتایج جستجو برای: bromodeoxyuridine

تعداد نتایج: 5050  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1970
D Schubert F Jacob

5-Bromodeoxyuridine induces the differentiation of mouse neuroblastoma C1300 to cells that morphologically resemble mature neurons. The induced differentiation can take place in the absence of DNA synthesis. This suggests that the halogenated pyrimidine need not be incorporated into DNA to alter the phenotype of the cell.

Journal: :Neurology 2001
Y Li J Chen L Wang M Lu M Chopp

OBJECTIVE To measure the therapeutic efficacy for the treatment of stroke with intra-arterial administration of bone marrow stromal cells (MSC). BACKGROUND MSC have characteristics of stem and progenitor cells. The hypothesis that MSC injected into the internal carotid artery after stroke enter into ischemic brain and improve neurologic recovery was tested. METHODS Twenty-five adult Wistar ...

Journal: :Anesthesiology 2010
Greg Stratmann Jeffrey W Sall Joseph S Bell Rehan S Alvi Laura d V May Ban Ku Mitra Dowlatshahi Ran Dai Philip E Bickler Isobel Russell Michael T Lee Margit W Hrubos Cheryl Chiu

BACKGROUND Roughly, 10% of elderly patients develop postoperative cognitive dysfunction. General anesthesia impairs spatial memory in aged rats, but the mechanism is not known. Hippocampal neurogenesis affects spatial learning and memory in rats, and isoflurane affects neurogenesis in neonatal and young adult rats. We tested the hypothesis that isoflurane impairs neurogenesis and hippocampal fu...

Journal: :Proceedings of the National Academy of Sciences 1973

Journal: :The Japanese Journal of Gastroenterological Surgery 1988

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