نتایج جستجو برای: bronchial hyper
تعداد نتایج: 46387 فیلتر نتایج به سال:
АСТМА ТА АЛЕРГІЯ, No 4 • 2013 Bronchial asthma (BA) – is a chronic disease caused by increased sensitivity of the bronchi to various kinds of stimulation. BA manifests itself by attacks caused by bronchial obstruction and stop autonomously or as a result of treatment. BA occurs with alternating exacerbations and remissions. During remission the disease may not manifest. Exacerbation is usually ...
In the last 10 years much interest has been directed towards the relationship between upper and lower airways, in particular between rhinitis and asthma. Several clinical and epidemiological studies have shown a strong association between rhinitis and asthma. Rhinitis has been demonstrated to be a major risk for asthma occurrence [1], with rhinitis often preceding the onset of asthma both in at...
BACKGROUND Phospholipase Cε (PLCε) is an effector of Ras and Rap small GTPases and expressed in non-immune cells. It is well established that PLCε plays an important role in skin inflammation, such as that elicited by phorbol ester painting or ultraviolet irradiation and contact dermatitis that is mediated by T helper (Th) 1 cells, through upregulating inflammatory cytokine production by kerati...
Data extraction 2 reviewers independently extracted data on study design, patient characteristics, details of the intervention, study duration, outcomes, and quality. Outcomes included lung function, quality of life measures, symptom scores, drugs for additional relief, acute exacerbation, days off work or school, treatment failure, patient compliance, patient preference, adverse effects, bronc...
Ten years ago most researchers in Western countries knew what caused asthma, and we knew how to prevent it.1 Asthma was an atopic disease caused by allergen exposure. The fundamental etiological mechanism was that allergen exposure, particularly in infancy, produced atopic sensitization and continued exposure resulted in asthma through the development of eosinophilic airway inflammation, bron...
The most appropiate management for bronchial asthma is the control of airway inflammation. Corticosteroids are the most effective anti-inflammatory drugs available, but they have a number of side effects; most of these are dose-dependent. In children, asthma control should be accomplished with low steroid doses possibly given by inhalation. In a double-bind placebo-controlled crossover study a ...
OBJECTIVE Risk factors related to the outcome of childhood asthma are not yet well established. We aimed to investigate the long-term outcome for children with asthma to determine the risk factors in predicting persistence of disease. METHODS Sixty-two children with asthma were evaluated retrospectively at the end of a 10-year follow-up. Patients were asked to complete a questionnaire request...
BACKGROUND Exposure to ambient air pollution and bronchiolitis are risk factors for asthma. The aim of this study was to investigate the effect of air pollution on the development of asthma in children with past episodes of bronchiolitis. METHODS A prospective 2-year follow-up survey consisting of parental responses to the International Study of Asthma and Allergies in Childhood (ISAAC) quest...
BACKGROUND A very weak relationship has been reported between the health-related quality of life (HRQL) of patients with asthma and their degree of airway hyper-responsiveness (AHR), evaluated in terms of sensitivity. However, this relationship still has not been sufficiently explored for bronchial reactivity indices. OBJECTIVES To analyse the relationship between bronchial reactivity and sen...
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