According to current guidelines regarding the hospital management of exacerbations of chronic obstructive pulmonary disease (COPD), short-acting inhaled 2 agonists are generally the preferred bronchodilators (evidence grade A).1 In the absence of a prompt response to those drugs, addition of a short-acting anticholinergic bronchodilator is recommended, although the effectiveness of this combina...

Pulmonary function tests were performed before and after inhalation of 1.3 mg of metaproterenol sulfate or 150 microgram of isoproterenol hydrochloride by 40 asthmatic and 40 normal subjects. PHysiologic measurements included spirometric testing, plethysmographic studies, and maximal expiratory flow-volume curves obtained after inhalation of air and a mixture of 80 percent helium and 20 percent...

Atrial natriuretic peptide (ANP) has been shown to be an effective bronchodilator when given intravenously, but its efficacy by inhalation has not been assessed. In the first part of the current study, six asthmatic subjects, mean (SEM) forced expiratory volume in one second (FEV1) 2.09 (0.30) l, received 0.1 and 1 mg atrial natriuretic peptide by inhalation, and in the second study five subjec...

The effectiveness and safety of fixed dual long-acting bronchodilators for chronic obstructive pulmonary disease (COPD) patients have been well established; however, there is a paucity clinical comparison in with COPD treatment. aim the current study was to compare three once-daily bronchodilator agents COPD. Patients diagnosed treated beta-agonist (LABA) + muscarinic antagonist (LAMA) fixed-do...

Bronchodilators are central in the treatment of of airways disorders. They are the mainstay of the current management of chronic obstructive pulmonary disease (COPD) and are critical in the symptomatic management of asthma, although controversies around the use of these drugs remain. Bronchodilators work through their direct relaxation effect on airway smooth muscle cells. at present, three maj...

Nepeta L. is one of the important genus in Lamiaceae family. It includes ca. 300 herbaceous species and mostly grows Eurasia. represented Turkey by 40 taxa these 16 are endemic. commonly utilized traditional medicine local people, primarily as spasmolytic, diuretic, bronchodilator agents. As a consequence studies on taxa, terpenoids flavonoids have been identified most common components. In thi...

The delivery of bronchodilators with metered-dose inhaler (MDI) in mechanically ventilated patients has attracted considerable interest in recent years. This is because the use of the MDI has several advantages over the nebulizer, such as reduced cost, ease of administration, less personnel time, reliability of dosing and a lower risk of contamination. A spacer device is fundamental in order to...

Background. Treatment and management strategies for asthma in children are generally consistent internationally, but prescription of antiasthma drugs differs among countries. The objective of this study was to examine the prescribing patterns of antiasthma drugs, particularly controller medications, in children. Methods. A retrospective cohort study was performed in children with asthma using a...

STUDY OBJECTIVES Increasing morbidity due to asthma and antimicrobial resistance among human pathogens are both major public-health concerns. Numerous studies describe the overuse of antibiotics in general populations and underuse of anti-inflammatory medications by asthmatic patients. However, little is known about the relationship between asthma medication and antibiotic use in asthmatics. Sp...