From GWAS to genome sequencing: complementary approaches to identify melanoma predisposition genes S MacGregor, KM Brown, M Stark, M Gartside, S Woods, V Bonazzi, L Aoude, K Dutton-Regester, S Tyagi, J Liu, DL Duffy, J Palmer, A Cust, H Schmid, J Symmons, E Holland, C Agha-Hamilton, K Holohan, D Youngkin, E Gillanders, MA Jenkins, J Kelly, DC Whiteman, R Kefford, G Giles, B Armstrong, J Aitken,...

A 41-year-old non-diabetic hypertensive male with chronic kidney disease (Stage V secondary to chronic interstitial nephritis) on maintenance haemodialysis presented with a recent onset of pain in the right lower limb. An X-ray of the lower leg showed a solitary, lytic soap bubble-like mass in the lower end of the fibula (Figure 1). Labs showed a serum creatinine of 11.4 mg/dL, blood urea 124 m...

We report for the first time levels of persistent organic pollutants in marine bird eggs from an oceanic island in the Indian Ocean, the world's third largest ocean. Ten eggs each of the Common Noddy, also known as the Brown Noddy (Anous stolidus), and Sooty Tern (Sterna fuscata) were collected from Ile Cocos off the coast of the island of Rodrigues, located 560 km east of the island of Mauriti...

Approximately 200 samples of rice (including white, brown, red, black, basmati and jasmine, as well as wild rice) from several different countries, including the United States, Canada, Pakistan, India and Thailand, were analysed for aflatoxins, ochratoxin A (OTA) and fumonisins by separate liquid chromatographic methods in two different years. The mean concentrations for aflatoxin B(1) (AFB(1))...

Recommendation 1161 Standardisation of labial salivary gland histopathology in clinical trials in primary Sjögren’s syndrome B A Fisher, R Jonsson, T Daniels, M Bombardieri, R M Brown, P Morgan, S Bombardieri, W-F Ng, A G Tzioufas, C Vitali, P Shirlaw, E Haacke, S Costa, H Bootsma, V Devauchelle-Pensec, T R Radstake, X Mariette, A Richards, R Stack, S J Bowman, F Barone, on behalf of the Sjögre...

UNLABELLED BACKGROUND Anabolic androgenic steroids, such as stanozolol, are typically misused by athletes during preparation for competition. Out-of-competition testing presents a unique challenge in the current anti-doping detection system owing to logistic reasons. Analysing hair for the presence of a prohibited drug offers a feasible solution for covering the wider window in out-of-compet...