Brucellosis is a zoonosis caused by the bacteria belonging to the genus Brucella. 1 Currently there are six recognized species of Brucellaebased on phenotypic characteristics, antigenic variations and prevalence of infection in different animal hosts. Brucella abortusin cattles, Brucella melitensis in sheep and goats, Brucella suis in pigs, Brucella canis in dogs, Brucella ovis in sheep and Bru...

Brucella endocarditis (BE) is a rare but life threatening complication of brucellosis. We present a case report of a patient with relapsing brucellosis complicated with aortic valve endocarditis. The patient underwent valve replacement and required prolonged antibiotic treatment because of rupture of the noncoronary leaflet and development of congestive heart failure. Since the onset of endocar...

Brucellosis is a common zoonotic infection worldwide caused by Brucella species. Central nervous system involvement is a serious complication of brucellosis, and the clinical presentation is quite heterogeneous. The genitourinary system may be affected. Epididymo-orchitis is the most common type of urinary tract involvement, which can cause serious complications. Herein, we present a case of br...

We evaluated the association between the mean platelet volume (MPV) and monocyte/lymphocyte ratio (MLR) with brucella-caused epididymo-orchitis to determine if they could be used to differentiate between brucella and non-brucella epididymo-orchitis. The charts of 88 patients with non-brucella and 14 patients with brucella epididymo-orchitis were retrospectively reviewed. Brucellosis was diagnos...

Brucellosis is an endemic zoonotic disease around the world such as Iraq, Turkey, and Iran. Brucella is brought into attention by affecting various organs thorough complications, but thyroiditis is a rare one. Here, we present a case of Brucellosis with neck discomfort and odynophagia who developed thyroiditis and was treated by antibiotic and corticosteroid therapy. This case report aims to dr...

Eighty feral swine were trapped from a herd that had been documented to be seropositive for Brucella and which had been used for Brucella abortus RB51 vaccine trials on a 7,100-hectare tract of land in South Carolina. The animals were euthanized and complete necropsies were performed. Samples were taken for histopathology, Brucella culture, and Brucella serology. Brucella was cultured from 62 (...

Brucellosis is a zoonotic infection with a worldwide distribution, endemic in the Mediterranean region, and is associated with high morbidity in humans [1,2]. Osteoarticular complications are the most common focal complications of Brucella spp. infection [3]. These complications commonly affect the axial skeleton, with vertebral spondylitis accounting for 35%–50% of all osteoarticular complicat...

The influence of growth medium and incubation conditions on the detection of Bilophila wadsworthia beta-lactamase was tested with Cefinase and Cefinase Plus disks. The tests involved aerobic and anaerobic incubation with conventional disk and quantitative tube assays. The production of beta-lactamase was correlated with penicillin G, ampicillin, and ampicillin-sulbactam MICs and inhibition zone...

A latex coagglutination assay was developed to identify rough (R) isolates of Brucella. Latex beads were coated, via protein A, with either an anti-Brucella rough-lipopolysaccharide (R-LPS) monoclonal antibody (MAb) or an anti-Brucella 25-kDa outer membrane protein (Omp25) MAb. Slide agglutination tests were done for 68 strains of Brucella spp., including type strains of all biovars as well as ...

Background: Human brucellosis is a zoonotic disease caused by Brucella melitensis, Brucella abortus, and Brucella suis. Brucella causes a chronic disease, which subverts the immune defense system of their hosts. In this study, the prevalence of an important Brucella virulence determinant, PrpA, which can modulate immune response, was determined in human isolates. Methods: Polymerase chain reac...