BACKGROUND An association of bullous pemphigoid with neurological disorders has been reported. The objectives of this study were to review the clinical characteristics of patients with bullous pemphigoid and compare the association between bullous pemphigoid and various neurological disorders and comorbidities. METHODS This was a retrospective case-control study involving 43 patients with bul...

Bullous dermatoses are a variety of autoimmune skin diseases that are characterized by the presence of bullae or blisters. Most of these diseases are associated with substantial morbidity, and a few may result in death. Although most general approaches to the treatment and diagnosis of these entities are similar, the diagnosis of the specific disease is important, because the most appropriate d...

Autoimmune bullous diseases result from an immune response to molecular components of the desmosome or basement membrane. Bullous diseases are associated with a high degree of morbidity and occasional mortality. Therapy of bullous diseases consists of suppressing the immune system, controlling inflammation and improving healing of erosions. The therapeutic agents used in the treatment of bullou...

A 34-year-old black man presented to the emergency department with right-sided pleuritic chest pain, productive cough, low grade fever, and dyspnea. He had a history of emphysema, deep vein thrombosis, protein C and S deficiency, and inferior vena cava filter. His physical exam was significant for fever, tachypnea, tachycardia, and decreased breath sounds over the right upper and middle lung fi...

Autoimmune bullous diseases are a group of cutaneous disorders characterised by skin blistering or erosions as a result of development of autoimmunity. It can be classified according to the anatomical sites of blister into two types: intraepithelial and subepidermal. It can be subdivided further according to the clinical features, type and location of immunoreactants found on skin biopsy (Table...

The burden of COPD in the United States is tremendous. This disease not only among leading causes mortality annually, but also takes a heavy financial toll.1 Bullous emphysema severe variant COPD. primary identified risk factor for bullous tobacco use; however, impact other substances clearly delineated.2 case presents patient diagnosed with at age 33 substantial progression over course 12 year...

Background: Bullous pemphigoid (BP) is the most common autoimmune bullous disease and it primarily affects elderly population. It typically presents with tense bullae severe pruritus. Non-bullous a subtype of BP characterized by lacking typical formation different presentations including erythematous, eczematous, urticarial, polycyclic, targetoid, nodular, lichenoid, vesicular erythrodermic. Ai...

Bullous pemphigoid (BP) is the most common autoimmune bullous disease.1 The association between BP and psoriasis has been frequently reported.2 histopathologic serologic findings in patients with include a subepidermal blister eosinophils3,4 BP180-noncollagenous 16A (NC16A) reactivity, demonstrated using enzyme-linked immunosorbent assay (ELISA).1 Uncommonly, histopathology of may be rich neutr...

OBJECTIVE Autoimmune bullous diseases are heterogeneous diseases and the differentiation between the various bullous disease is important for treatment and prognosis. Direct immunofluorescence microscopy is still the gold standard in differentiating these diseases. Our aim was to determine the diagnostic accordance between clinical and histopathological/direct immunofluorescence diagnosis of pa...

Lichen planus pemphigoides (LPP) is a rare autoimmune blistering disease that is characterized by the development of vesico-bullous skin lesions in patients with lichen planus. The histopathology of LPP reveals a sub_epidermal blister with linear deposition of IgG and /or C3 along the dermal_epidermal junction (DEJ) upon direct immunofluorescence (DIF). We hereunder describe a case of lichen pl...