Apolipoproteins are a group of proteins that found on the surface lipoprotein particles and involved in lipid metabolism. Lipoproteins complexes lipids transport bloodstream, triglycerides to peripheral tissues, reverse cholesterol from tissues liver for excretion. They important biomarkers metabolism known be associated with an increased risk CVD. This study aims assess effect gender some apol...

The structure and function of plasma lipoproteins have received increasing attention in the past few years. The recognition of the importance of the protein moiety for the structural stability and metabolism of these conjugated macromolecules has stimulated this field of research and has emphasized the careful characterization of the apo-lipoproteins for a better understanding of lipid transpor...

The present study aimed to find out the effect of Metformin drug on some biochemical parameters, including Glucose and lipid profile: Cholesterol, Triglycerides, High density lipoprotein HDL-CH, low LDL-C Male albino rats were used in this study.
 results showed that development diabetes induced by alloxan led a significant increase levels glucose, cholesterol, triglycerides, low-density c...

The goals of this study were to investigate the effects of the callipyge (CLPG) phenotype on serum creatinine and lipid profiles of growing lambs. Preliminary studies in our laboratories indicated that creatinine may have utility in distinguishing the CLPG phenotype and that expression of the CLPG gene altered concentrations of serum total cholesterol (TC). As a result, in this study, we examin...

background: preliminary clinical trials showed that ginger improved lipid profile in type 2 diabetes patients (t2d). this trial was carried out to determine the effect of ginger on blood lipid and lipoproteins in t2d. methods: this is a randomized, double-blind, placebo-controlled trial on 88 t2d conducted in. the patients were randomly divided into two groups of ginger (gg) and placebo (pg), t...

A rapid and sensitive method for determining protein concentrations using fluorescamine has been characterized for use in the analysis of intact lipoproteins. It was shown that there is no interference with the assay due to the presence of lipid-associated turbidity or primary amine content. The assay was shown to be sensitive to as little as 0.3 p g of lipoprotein and to yield similar results ...

Natural abundance 13C NMR spectra of high density, low density, and very low density lipoproteins isolated from human plasma have been recorded and assigned, and the spin lattice relaxation times (T1) of some well resolved resonances have been determined. The laC NMR spectra reflect differences in protein-lipid ratios and in lipid composition between the three classes of lipoproteins. All three...

HDL (high-density lipoproteins) remove cell cholesterol and protect from atherosclerosis. The major HDL protein is apoA-I (apolipoprotein A-I). Most plasma apoA-I circulates in lipoproteins, yet ~5% forms monomeric lipid-poor/free species. This metabolically active species is a primary cholesterol acceptor and is central to HDL biogenesis. Structural properties of lipid-poor apoA-I are unclear ...

A rapid and sensitive method for determining protein concentrations using fluorescamine has been characterized for use in the analysis of intact lipoproteins. It was shown that there is no interference with the assay due to the presence of lipid-associated turbidity or primary amine content. The assay was shown to be sensitive to as little as 0.3 p g of lipoprotein and to yield similar results ...

A clear picture of lipoprotein metabolism is essential for understanding the pathophysiology of atherosclerosis. Many students are taught that low-density lipoprotein-cholesterol is "bad" and high-density lipoprotein-cholesterol is "good." This misconception leads to students thinking that lipoproteins are types of cholesterol rather than transporters of lipid. Describing lipoproteins as partic...