PURPOSE To investigate use of an improved ocular tear film analysis protocol (OPI 2.0) in the Controlled Adverse Environment (CAE(SM)) model of dry eye disease, and to examine the utility of new metrics in the identification of subpopulations of dry eye patients. METHODS Thirty-three dry eye subjects completed a single-center, single-visit, pilot CAE study. The primary endpoint was mean break...

OBJECTIVES Coronary artery ectasia (CAE) has been defined as a dilated artery luminal diameter that is at least 50% greater than the diameter of the normal portion of the artery. Isolated CAE is defined as CAE without significant coronary artery stenosis and isolated CAE has more pronounced inflammatory symptoms. Neutrophil to lymphocyte ratio (NLR) is widely used as a marker of inflammation an...

A total of 158 volunteers each received 21 repeated oral doses of 500 mg of cefuroxime axetil (CAE) during four comparative cross-over trials. Pharmacokinetics were studied in 8 volunteers (CAE versus ampicillin), relative bioavailability and tolerance were studied in 100 volunteers (CAE versus pivmecillinam and CAE versus pivampicillin), and tolerance alone was studied in 50 volunteers (CAE ve...

conclusions presence of cae in patients with cas increases its cardiovascular event rate. isolated cae is not a benign finding and mi can occur. risk factors of cae are similar to cas, but c/s is more associated with cae than cas. dm is seen in cae patients less than cas. results hypertension (htn), dyslipidemia (dlp), and male sex were matched in both groups without significant difference. cig...

OBJECTIVE The aim of this study was to investigate the relationship between platelet-to-lymphocyte ratio (PLR), an easily available inflammatory marker, and coronary artery ectasia (CAE). METHODS After applying the exclusion criteria, the retrospective study population consisted of 330 patients, including 110 patients with isolated CAE, 110 with obstructive coronary artery disease (CAD), and ...

Neuropsychological studies indicate that new-onset childhood absence epilepsy (CAE) is associated with deficits in attention and executive functioning. However, the contribution of these deficits to impaired academic performance remains unclear. We aimed to examine whether attention and executive functioning deficits account for the academic difficulties prevalent in patients with new-onset CAE...

OBJECTIVE To evaluate the accuracy of a computer-aided evaluation program (CAE) of breast MRI for the assessment of residual tumor extent and response monitoring in breast cancer patients receiving neoadjuvant chemotherapy. MATERIALS AND METHODS Fifty-seven patients with breast cancers who underwent neoadjuvant chemotherapy before surgery and dynamic contrast enhanced MRI before and after che...

The antisickling effects of the extracts of three vegetables highly consumed in Nigeria were investigated which included: Allium cepa (Onion), Allium sativum (Garlic) and Telferia occidentalis (Ugu). The extracts were partitioned into, the fat-soluble (FAS), the water-soluble (WAS), the butanol-soluble (BUS) and the crude aqueous extracts (CAEs) respectively. Free amino acid concentrations of t...

BACKGROUND Previous studies have demonstrated that inflammation, neurohormonal process and cardiovascular risk factors are associated with the development of coronary artery ectasia (CAE). However, the underlying mechanisms responsible for ectasia formation are not fully understood. The neutrophil to lymphocyte (N/L) ratio has recently emerged as a new inflammation marker for cardiovascular dis...