We studied calretinin-immunoreactive (IR) fibers and cells in the canine superior colliculus (SC) and studied the distribution and effect of enucleation on the distribution of this protein. Localization of calretinin was immunocytochemically observed. A dense plexus of anti--calretinin-IR fibers was found within the upper part of the superficial gray layer (SGL). Almost all of the labeled fiber...

Breast carcinoma is the second most common cancer following lung cancer. The incidence of accounts for 24.2% and death about 15% among females. There are various prognostic predictive factors assessing patient encountering breast. Among factors, histological subtype molecular play a key role. calretinin expression in breast was seen high-grade carcinomas basal like Calretinin predominantly note...

The present study describes the distribution and structural features of calretinin-immunoreactive neurons and fiber plexuses in the cerebral cortex of a lacertid lizard, at the light and electron microscopic levels, and also examines the colocalization of calretinin with parvalbumin and gamma-aminobutyric acid (GABA) in certain cortical regions. Calretinin-immunoreactive neurons are present thr...

Granular cell tumors (GCTs) typically express S-100 protein, which has been used as a marker in differential diagnosis. Calretinin, a calcium-binding protein related structurally to S-100, and inhibin, a polypeptide hormone secreted primarily by ovarian granulosa cells and testicular Sertoli cells and functioning as an inhibitor for pituitary follicle-stimulating hormone secretion, are potentia...

The cover image is based on the Research Article Calretinin and calbindin architecture of midline thalamus associated with prefrontal-hippocampal circuitry by Tatiana D. Viena et al., https://doi.org/10.1002/hipo.23271.

The calcium-binding protein calretinin has emerged as a useful marker for the identification of mesotheliomas of the epithelioid and mixed types, but its putative role in tumor development has not been addressed previously. Although exposure to asbestos fibers is considered the main cause of mesothelioma, undoubtedly, not all mesothelioma patients have a history of asbestos exposure. The questi...

Calretinin (CALB2) is a diagnostic marker for epithelioid mesothelioma. It is also a prognostic marker since patients with tumors expressing high calretinin levels have better overall survival. Silencing of calretinin decreases viability of epithelioid mesothelioma cells. Our aim was to elucidate mechanisms regulating calretinin expression in mesothelioma. Analysis of calretinin transcript and ...

Amaç: Mezotelyoma ile akciğer adenokarsinomunun ayırıcı tanısında morfolojik bulgular yetersizdir. İmmünohistokimyasal inceleme en iyi yardımcı yöntemdir. Çalışmada mezotelyoma uygun belirteçlerin belirlenmesi amaçlanmıştır. Gereç ve Yöntem: Bu çalışmada hastanemizde tanı almış adenokarsinomu olgularına ait patoloji arşivi incelenerek bu olgularda tanıya giderken kullanılan calretinin, D2-40, p...

BACKGROUND The Ca(2+)-binding protein calretinin is currently used as a positive marker for identifying epithelioid malignant mesothelioma (MM) and reactive mesothelium, but calretinin's likely role in mesotheliomagenesis remains unclear. Calretinin protects immortalized mesothelial cells in vitro from asbestos-induced cytotoxicity and thus might be implicated in mesothelioma formation. To furt...