Contemporary endodontics and the future of endodontics are based on regenerative strategies. Success of these regenerative endodontic treatments depends on disinfection of the root canal system. Current research in endodontics focuses on identifying the optimal methods of disinfection of root canal systems to achieve predictable results in revascularization therapy. Although the use of sodium h...

microorganisms play a major role in the initiation and perpetuation of pulpal and periapical disease. in order to predictably achieve a bacteria-free root canal system, it is necessary to use intracanal medicaments. calcium hydroxide is the most common intracanal medicaments. it is effective against primary infections. however, its effectiveness against enterococcus faecalis and candida albican...

An important consideration in endodontic treatment is the elimination of microorganisms, including fungi, from the complex threedimensional root canal system. Yeasts can be detected in 7-17% of infected root canals. Candida albicans (CA) has a major role in endodontic treatment failure as the most important fungus isolated from the root canal system. C. albicans has been associated with root ca...

Periapical lesions of endodontic origin may develop asymptomatically and become extensive. Treatment options to manage such lesions range from non-surgical root canal treatment and/or apical surgery to extraction. A high percentage of complete and partial healing of extensive perapical lesions following conventional endodontic therapy has been reported. The case reports in this article describe...

AIM To compare the efficiency of removing calcium hydroxide [Ca(OH)(2)]/chlorhexidine (CHX) (gel), Ca(OH)(2)/CHX (solution) and Ca(OH)(2)/saline pastes with the use of instrumentation and irrigation with sodium hypochlorite and ethylene diamine tetraacetic acid (EDTA) solutions. Moreover the role of the patency file in the cleanliness of the apical third of the root canal was evaluated. METHO...

background and aims. triple antibiotic paste (tap) is widely used in endodontics for root canal disinfection, particularly in regenerative procedures. the aim of this in vitro study was to evaluate the antimicrobial effects of different concentrations of tap at 1-, 2-, 3-, and 4-week intervals on mature enterococcus faecalis biofilm. materials and methods. a total of 287 extracted one-rooted hu...

objective: in necrotic immature teeth, intra canal medicaments such as triple antibiotic paste (tap) and calcium hydroxide (ch) are used for root canal disinfection and regeneration treatment. however, the effect of these medicaments on dental pulp fibroblasts has yet to be known. this study aimed to assess the cytotoxicity of ch and tap against cultured human dental pulp fibroblasts (hdpfs) ob...

The important requisite of root canal treatment is that canals should be free microorganisms, which plays major role in success treatment. Usage intracanal medicament inside will help the reduction microbes system. Intracanal medicaments also inter-appointment pain. A survey was conducted among dental practitioners and non-endodontic specialists Tamilnadu to evaluate knowledge awareness medicam...

The purpose of this paper is to discuss critically the antibacterial efficacy of intracanal medicaments on bacterial biofilm. Longitudinal studies were evaluated by a systematic review of English-language articles retrieved from electronic biomedical journal databases (MEDLINE, EMBASE, CENTRAL) and handsearching records, using different matches of keywords for root canal biofilm, between 1966 a...