نتایج جستجو برای: cancer causing genes
تعداد نتایج: 1370181 فیلتر نتایج به سال:
The prostate is a small gland located below the bladder and upper part of the urethra. In developed countries prostate cancer is the second common cancer (after skin cancer), and also the second leading cause of cancer death (after lung cancer) among men. The several studies have been shown prostate cancer familial aggregation. The main reason for this aggregation is inheritance included genes....
Background & Aims: Prostate cancer (PCa) is the second most common cancer in men worldwide. The identification of sensitive and specific biomarkers in tissue and serum is of utmost importance to reduce the mortality of prostate cancer. Since that, early detection of cancer has an important role in treatment, in this study we tried to identify genes that could potentially effective in early...
Epigenetic modification is one of the effective factors in tumorigenesis. Epigenetic processes, especially aberrant DNA methylation, play important role in thyroid cancer, and many tumor suppressor genes including PTEN, RASSF1A and TIMP3 are aberrantly methylated and silenced in thyroid cancer. Because of the specified pattern of DNA methylation in various tumor cells, it is suggested that thes...
abstract background and objective: baba2 and hpa genes are involved in adherence of helicobacter pylori (h.pylori) to gastric mucosal tissue. this study aimed to investigate the frequency of these genes in isolates of h. pylori from gastric biopsies and their relationship with gastritis, peptic ulcer and gastric cancer. methods: gastric biopsy samples were obtained from patients wit...
The diverse, specialized genes in today’s lifeforms evolved from a common core of ancient, elementary genes. However, these genes did not evolve individually: gene expression is controlled by a complex network of interactions, and alterations in one gene may drive reciprocal changes in its proteins’ binding partners. We show that the topology of a leukemia gene regulatory network is strongly co...
Cancer is among the diseases causing death, in which, cells uncontrollably grow and reproduce beyond cell regulatory mechanism. In this disease, some genes are initiators of abnormalities then transmit them to other through protein interactions. Accordingly, these known as cancer driver (CDGs). regard, several methods have been previously developed for identifying genes. Most computational-base...
Submit Manuscript | http://medcraveonline.com The carcinogens, which is one of the causing factors of cancer, and mutations of some genes that supress cancer formation are known the most important contributing factors for cancer [1,2]. The risk of cancer can be diminished an average of 30-40% with an adequate diet and exercise. Approximately 5 million people in the world would be protected by a...
Effects of fibromodulin protein expression on NFkB and TGFβ signaling pathways in liver cancer cells
Introduction: The incidence rate of liver cancer is continuously increasing. Currently, gene therapy is applied to improve various medical issues such as cancer treatment approaches. Correspondingly, fibromodulin involves in many biological and physiological processes through interaction with growth factors and signaling pathway receptors. The aim of this study was to investigate the effects of...
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