a radio assay employing 14c-uridine to measure the intracellular killing of candida albicans by phagocytes is presented. the principle of this new method is that after killing of candida albicans by phagocytes rna synthesis stops and therefore uridine uptake is diminished whilst viable candida in cultures would take up uridine and as a result, high cpm counts can be obtained within 135 min. of ...

This study was conducted to determine the proteinase, phospholipase, and biofilm forming abilities of Candida isolates in blood cultures of specimens from patients at the University Malaya Medical Center, Kuala Lumpur, Malaysia. Proteinase and phospholipase activities were detected in 93.7% and 73.3%, respectively, of 15 Candida albicans isolates. Amongst the 26 non-C. albicans Candida isolates...

The fungal pathogen Candida albicans is an opportunistic fungal pathogen that causes oral and vaginal mucosal infections as well as systemic disease. The ability of C. albicans to adhere to host surfaces is positively correlated with its pathogenicity. We prepared a polyclonal anti-Candida albicans antibody in chicken egg yolk (anti-C. albicans IgY) and investigated its in vitro effectiveness i...

Background and Purpose: Candida dubliniensis is closely related to the most pathogenic and prevalent yeast, namely C. albicans. Candida species can opportunistically overgrow in vulnerable individuals and cause a variety of diseases. The current study aimed to identify and isolate C. dubliniensis species present in the Candida albicans species complex identified in the oral cavity of drug abuse...

background recent evidences have revealed that in more than 65% of microbial infections, biofilms have critical roles. the ability of yeasts to form biofilms on surface of medical devices such as urine catheters is an important reason of the capability of these microorganisms to cause human disease. objectives the aim of this study was to isolate and identify yeasts on the surfaces of urine cat...

conclusions non-albicans candida should be considered as significant pathogens in burned patients with candidemia. results twenty-seven samples (6.7%) of the blood cultures from 13 patients (12%) were positive for candida species. candida parapsilosis (38%) and c. tropicalis (38%) were the most commonly found candida species, followed by c. albicans (15%) and c. guilliermondii (15%) in the pati...

PURPOSE The aim of the study was the determination of antifungal activity of new of 2,5 disubstituted amino-oksometyloso-arylo-thiadiazole (AOAT) derivatives against Candida albicans, non-Candida albicans. MATERIAL AND METHODS The determination of antifungal activity AOATs against 20 Candida albicans, 18 non-Candida albicans was performed. Isolates were from different ontocenoses of patients ...

Hasenclever, H. F. (U. S. Public Health Service, Bethesda, Md.), and William O. Mitchell. Antigenic studies of Candida. III. Comparative pathogenicity of Candida albicans group A, group B, and Candida stellatoidea. J. Bacteriol. 82:578-581. 1961.-Since the antigenic differences between Candida albicans group A and C. albicans group B had been established, the problem of a difference in pathogen...

BACKGROUND AND AIMS It is believed that adherence of Candida albicans to oral surfaces is a critical event in the coloni-zation and development of oral diseases such as candida-associated denture stomatitis. Although there is considerable infor-mation about the adherence of Candida albicans to buccal epithelial cells and prosthetic materials, there is very little infor-mation available about th...

background and objectives: vulvovaginal candidiasis is a common fungal infection among women during reproductive ages. although, candida albicans is accounted as the main etiologic agent of vaginitis, non- albicans species have arisen during last years. resistant to antifungal drugs especially, fluconazole has been more reported by researchers from around the world. the aims of this study were ...