BACKGROUND Community-acquired pneumonia (CAP) is a common childhood infection. CAP complications, such as parapneumonic empyema (PPE), are increasing and are frequently caused by antibiotic-resistant organisms. No clinical guidelines currently exist for management of pediatric CAP and no published data exist about variations in antibiotic prescribing patterns. Our objectives were to describe va...

BACKGROUND The BC Cancer Agency Gastro-intestinal Tumor Group supports one standard of care (SOC) chemotherapy regimen for metastatic esophagogastric adenocarcinoma-specifically, weekly cisplatin and 5-fluorouracil (5FU) infusion. All other regimens require Compassionate Access Program (CAP) approval for public funding. OBJECTIVES We examined response, toxicity, and survival after first-line ...

This report summarizes the presentations and discussions that took place at the Seventh Joint Meeting of the Korea-Japan Study Group of Prostate Cancer (K-J-CaP) and the Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE) held in Seoul, Korea, in September 2013. The original J-CaP and CaPSURE Joint Initiative has now been established since 2007 and since the initial collaborat...

OBJECTIVE The Japan Respiratory Society documented a new category of guidelines for nursing and healthcare-associated pneumonia (NHCAP), which is distinct from community acquired pneumonia (CAP). The objective of this study was to determine the epidemiological differences between NHCAP patients in a teaching university hospital and a community hospital. In addition, to clarify the strategy for ...

STUDY OBJECTIVE s: Consensus guidelines for the empirical treatment of community-acquired pneumonia (CAP) have been published. We investigated the following factors: (1) the degree of adherence to American Thoracic Society (ATS) and the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) guidelines; and (2) the influence of adhering to these guidelines on mortality and length of hospita...

BACKGROUND The choice of antibiotics to treat community-acquired pneumonia (CAP) is primarily empiric, and the effect of this choice on length of stay (LOS) and mortality is largely unknown. OBJECTIVE To examine the impact of antibiotic choice on these outcomes in general medical patients hospitalized with CAP. METHODS One hundred patients hospitalized with CAP were prospectively identified...

BACKGROUND Few studies evaluated the clinical outcomes of Community Acquired Pneumonia (CAP), Hospital-Acquired Pneumonia (HAP) and Health Care-Associated Pneumonia (HCAP) in relation to the adherence of antibiotic treatment to the guidelines of the Infectious Diseases Society of America (IDSA) and the American Thoracic Society (ATS) in hospitalized elderly people (65 years or older). METHODS...

OBJECTIVE Chemotherapy is one of the commonly used therapies for advanced gastric cancer. In this study, we performed a network meta-analysis on the efficacy and safety of common treatments to give evidences of their relative benefits. RESULTS 32 trials with 8550 patients and 20 regimens were included in this study. According to the results of primary outcomes, 5-FU plus OXA, 5-FU plus DOC, C...

Treatment with macrolides has been shown to have beneficial effects in chronic inflammatory airway diseases such as diffuse panbronchiolitis [2] and cystic fibrosis [3]. Whether adding macrolide therapy to the antibiotic regimen in patients with sepsis and CAP will result in a better outcome cannot be concluded from the study performed by RESTREPO et al. [1]. Their nonrandomised study did not p...

introduction: the aim of our study is evaluation of response rate of vad (vincristin, adriamycin and dexamethason) regimen as initial treatment in 40 new cases of multiple myeloma. this is the first systemic and classic report of vad regimen in iranian population. methods: all patients with at least stage 2 multiple myeloma or progressive disease after physical examination, para- clinical profi...