The article develops an understanding of public deliberations during a peace process, focusing on the interaction between the elite level negotiations and the “public peace process.” It does so by examining the dialogical mechanisms that are set to work in the public sphere once the elite consider the possibility of identifying the former enemies as allies or friends. These dialogical mechanism...

Poisons Information Centre, Department of Paediatrics and Child Health, Red Cross War Memorial Children’s Hospital and University of Cape Town, Cape Town, South Africa Centre for Occupational and Environmental Health Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa Department of Paediatrics and Child Health, Red Cross War Memorial Children’...

1Head Clinical Unit: Surgery, New Somerset Hospital, Cape Town, South Africa 2Senior Lecturer, University of Cape Town, Cape Town, South Africa 3Private Practice, Somerset West, South Africa 4Private Practice, Bellville, South Africa 5Private Practice, George and Consultant Surgeon George Provincial Hospital, South Africa 6Honorary Senior Lecturer, University of Cape Town, Cape Town, South Afri...

Glutathione S-transferase (GST) and multidrug resistance-associated proteins (MRPs) play major roles in drug resistance in melanoma. In this study, we investigated caffeic acid phenethyl ester (CAPE) as a selective GST inhibitor in the presence of tyrosinase, which is abundant in melanoma cells. Tyrosinase bioactivates CAPE to an o-quinone, which reacts with glutathione to form CAPE-SG conjugat...

The Cape Snoek, or Thyrsites atun, is a species of fish that has a significant presence in the history of the Western Cape and the development of Cape Town. The snoek is a lively creature that is historically, culturally, economically, and ecologically active in the Western Cape. I argue that in the case of the Cape snoek, the fish and the Cape are performed together; through acts of differenti...

Division of Human Genetics, Department of Pathology, Faculty of Health Sciences, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Anzio Road, Observatory, 7925, Cape Town, South Africa Department of Clinical Pharmacology, College of Health Sciences, University of Zimbabwe, P.O. Box A178, Avondale, Harare, Zimbabwe 3 International Centre for Genetic Engineering a...

Diabetic nephropathy (DN) is one of the most severe complications of diabetes mellitus. This study aimed to determine the effects and potential mechanism of caffeic acid para-nitro phenethyl ester (CAPE-pNO2), a derivative of caffeic acid phenethyl ester (CAPE), on DN; In vivo, intraperitoneal injections of streptozotocin (STZ) were used to induce diabetes in mice; then, the mice were intraperi...

Caffeic acid phenethyl ester (CAPE) is found in a variety of plants and well-known the active ingredient of the honeybee propolis. CAPE showed anti-inflammatory, anticarcinogenic, antimitogenic, antiviral, and immunomodulatory properties in several studies. The beneficial effects of CAPE on different health issues attracted scientists to make more studies on CAPE. Specifically, the anti-viral e...

The protective effects of Caffeic Acid Phenethyl Ester (CAPE) and intralipid (IL) on nephrotoxicity caused by acute Dichlorvos (D) toxicity were investigated in this study. Forty-eight Wistar Albino rats were divided into 7 groups as follows: Control, D, CAPE, intralipid, D + CAPE, D + IL, and D + CAPE + IL. When compared to D group, the oxidative stress index (OSI) values were significantly lo...

Ruud Hortensius , David Terburg , Barak Morgan , Dan J. Stein , Jack van Honk b,c,g and Beatrice de Gelder a,b,* a Brain and Emotion Laboratory, Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands b Department of Psychiatry and Mental Health, University of Cape Town, J-Block, Groote Schuur Hospital, Cape Town, South Af...