Ahalf century ago Roberts and Wearn' published their classical study on human hearts, which demonstrated that 1) capillaries multiply during postnatal growth to compensate for the increase in muscle fiber size, 2) muscle-to-capillary ratio attains a value of approximately 1:1 at maturity, and 3) this ratio persists throughout life. They also found that hypertrophied hearts of adults consistentl...

Ahalf century ago Roberts and Wearn' published their classical study on human hearts, which demonstrated that 1) capillaries multiply during postnatal growth to compensate for the increase in muscle fiber size, 2) muscle-to-capillary ratio attains a value of approximately 1:1 at maturity, and 3) this ratio persists throughout life. They also found that hypertrophied hearts of adults consistentl...

Oxygen is an essential part of the living organism. It is transported from blood to the body tissue by the systematic circulation and large part of it is stored in the blood flowing in capillaries. In this work we discuss a mathematical model for oxygen transport in tissues. The governing equations are established assuming that the blood is flowing along a co-axial cylindrical capillary inside ...

The integrity of the capillary membrane is essential to the maintenance of the circulation in a normal animal. Increased loss of plasma colloids through the capillary wall may be an important factor in the development of a pathologic state. In recent years, interest has centered upon abnormal capillary permeability, and local changes in permeability have been demonstrated in areas of trauma and...

In their 1993 report, MOSER AND BLOOR [1] described an array of microvascular ‘‘pulmonary hypertensive’’ lesions in patients with operable chronic thromboembolic disease. Although it was concluded that these findings in any one patient did not ‘‘preclude a positive haemodynamic and clinical result’’, these early observations became the foundation of our current understanding of the evolution of...

Breast cancer-related lymphedema (BCRL) is a frequent and debilitating complication of breast cancer treatment. The pathophysiology is complex and remains poorly understood; however, data suggest that changes in the peripheral circulation may contribute to edema formation. In 13 volunteers with unilateral BCRL, the following aspects of upper extremity peripheral circulation were examined: muscl...

The initial symptoms are probably caused by mechanical occlusion of multiple blood vessels with fat globules that are too large to pass through the capillaries. The vascular occlusion in fat embolism is often temporary or incomplete, as fat globules do not obstruct capillary blood flow completely because of their fluidity and deformability. The late presentation is thought to be a result of hyd...

The initial symptoms are probably caused by mechanical occlusion of multiple blood vessels with fat globules that are too large to pass through the capillaries. The vascular occlusion in fat embolism is often temporary or incomplete, as fat globules do not obstruct capillary blood flow completely because of their fluidity and deformability. The late presentation is thought to be a result of hyd...