In this work we demonstrate a label-free optical imaging technique to assess metabolic status and oxidative stress in human induced pluripotent stem cell-derived cardiomyocytes by two-photon fluorescence lifetime imaging of endogenous fluorophores. Our results show the sensitivity of this method to detect shifts in metabolism and oxidative stress in the cardiomyocytes upon pathological stimuli ...

Introduction: This study aimed to evaluate the effects of four-time inflation of the stent balloon at nominal pressure on optimal stent expansion in resistant lesions. Materials and Methods: This interventional study was conducted on 39 patients with coronary artery lesions, in whom Zotarolimus-eluting stents (N=20), Paclitaxel-eluting stents (N=11) and other stents (N=8) were deployed four tim...

introduction: this study aimed to evaluate the effects of four-time inflation of the stent balloon at nominal pressure on optimal stent expansion in resistant lesions. materials and methods: this interventional study was conducted on 39 patients with coronary artery lesions, in whom zotarolimus-eluting stents (n=20), paclitaxel-eluting stents (n=11) and other stents (n=8) were deployed four tim...

introduction while primary malignant tumors of the heart are rare, angiosarcomas are the most common cardiac malignant tumors. case presentation we describe a 23-year-old woman who presented with a right atrial mass, which was discovered to be a cardiac angiosarcoma. we demonstrate the use of several noninvasive imaging modalities along with pathology confirmation for the definitive and compreh...

Background Segmented balanced steady state free precession (bSSFP) cine imaging is the gold standard MRI technique for assessing ventricular systolic function. The image acquisition involves ECG gating and is ideally performed during breath-hold to reduce artifacts from myocardial and respiratory motion. Real-time radial imaging with parallel imaging technique GRAPPA reconstruction (radial GRAP...

Cardiac neuroimaging with (123)I-metaiodobenzylguanidine ((123)I-MIBG) has been officially used in clinical practice in Japan since 1992. The nuclear cardiology guidelines of the Japanese Circulation Society, revised in 2010, recommended cardiac (123)I-MIBG imaging for the management of heart failure (HF) patients, particularly for the assessment of HF severity and prognosis of HF patients. Con...

Cardiac ultrasound plays an important role in the imaging of hearts in basic cardiovascular research and clinical examinations. 3D ultrasound imaging can provide the geometry or motion information of the heart. Especially, the wrapping of cardiac fiber orientations to the ultrasound volume could supply useful information on the stress distributions and electric action spreading. However, how to...

Cardiac imaging is essential for the diagnosis and follow-up individuals with congenital heart disease (CHD). Currently echocardiography is the first-line investigation, although no single imaging technique is sufficient for complete evaluation of cardiac anatomy and physiology in these patients. Increasingly, adults with CHD are referred for cardiac magnetic resonance (CMR) imaging. Thehigh sp...

PURPOSE First, to assess the feasibility of a protocol involving stress-induced perfusion evaluated at computed tomography (CT) combined with cardiac CT angiography in a single examination and second, to assess the incremental value of perfusion imaging over cardiac CT angiography in a dual-source technique for the detection of obstructive coronary artery disease (CAD) in a high-risk population...