A multi-factor experimental design for evaluating random-access analyzers has been developed and tested for the Ciba Corning "550 Express" random-access analyzer. The 12-sample design estimates imprecision, slope, nonlinearity, linear drift, and reagent carryover to the next assay. The design was constructed so that estimates of the factors' effects are almost entirely uninfluenced by each othe...

A major instrumental limitation to rapid, "random-access" clinical analysis has been cross-contamination at sampling and reagent probes. Use of an immiscible, nonreactive fluid as a positive barrier between the liquid sample and reagent and the interior and exterior surfaces of their respective probes provides an inert, deformable surface that both prevents carryover and ensures accurate delive...

Carryover effects of emotions that lead to biases in social judgments are commonly observed. We suggest that such effects may be influenced by the ability to engage or disengage attention from emotional stimuli. We assessed the ability to activate and inhibit attention to anger stimuli, experimentally induced anger in a demanding task, and measured social judgment toward an ambiguous target. Re...

Tonal coarticulation is universally found to be greater in extent in the carryover direction compared to the anticipatory direction ([1], [2], [3], [4], [5]) leading to assimilatory processes. In general, carryover coarticulation has been understood to be due to intertio-mechanical forces, and, anticipatory effects are seen to be a consequence of parallel activation of articulatory plans ([6])....

This study quantifies acoustic variation of vowel nasalization arising from phonetic context in American English with an emphasis on carryover contexts. While qualitative articulatory trajectories and phonetic descriptions suggest that a vowel is nasalized in carryover contexts, few acoustic studies have examined this issue. Our acoustic analyses investigate the vowel /i/ and show that: (1) a v...

During the past two decades PCR and several other DNA/RNA amplification techniques have become important diagnostic tools in clinical laboratories. Amplification products contamination has been the main impediment to using these techniques routinely in diagnostic laboratories. Over the years, several creative pre- and post-amplification methods have been developed that prevent amplicon carryove...