BACKGROUND In the present study, we examined spinal glial cell activation as a central nervous system mechanism of widespread mechanical hyperalgesia in rats that experienced chronic post-cast pain (CPCP) 2 weeks after cast immobilization. Activated spinal microglia and astrocytes were investigated immunohistologically in lumbar and coccygeal spinal cord segments 1 day, 5 weeks, and 13 weeks fo...

BACKGROUND Cast immobilization induces mechanical hypersensitivity, which disturbs rehabilitation. Although vibration therapy can reduce various types of pain, whether vibration reduces immobilization-induced hypersensitivity remains unclear. OBJECTIVE The purpose of this study was to investigate the preventive and therapeutic effects of vibration therapy on immobilization-induced hypersensit...

BACKGROUND Flexible intramedullary nailing (IMN) is a valuable tool in the treatment of femoral fractures in school-age children, whereas spica cast immobilization has been the standard of care for younger children. We compared these treatment modalities in a group of preschool-age children (four to five years of age). METHODS A retrospective cohort of consecutive patients, four to five years...

Muscle disuse induces a wide array of structural, biochemical, and neural adaptations in skeletal muscle, which can affect its function. We recently demonstrated in patients with an orthopedic injury that cast immobilization alters the resting P(i) content of skeletal muscle, which may contribute to loss of specific force. The goal of this study was to determine the direct effect of disuse on t...

Management of a wide variety of musculoskeletal conditions requires the use of a cast or splint. Splints are noncircumferential immobilizers that accommodate swelling. This quality makes splints ideal for the management of a variety of acute musculoskeletal conditions in which swelling is anticipated, such as acute fractures or sprains, or for initial stabilization of reduced, displaced, or uns...

In brief: Easily mistaken for an ankle fracture during the initial examination, medial subtalar dislocation-also known as 'basketball foot'-requires plaster immobilization for no more than 3 weeks. To extend immobilization beyond this time can lead to reduced range of motion in the subtalar joint, making it difficult for the athlete to resume sports activities. Encouraging toe motion while the ...

the effect of tamoxifen citrate on bone mass in immobilization osteoporosis was studied in 10 dogs.osteoporosis was induced by fiberglass cast immobilization of the right hind-limb for 28 days, while the lefthind-limb served as a non-immobilized control. five dogs received tamoxifen citrate (1.5 mg/kg per os) once daily for 28 days; five dogs received no treatment. all dogs were euthanized on d...

The energy cost of walking with axillary crutches and each of three types of plaster casts (long, short, and cylinder) on the lower extremity was measured in twenty normal adult men. The knee and ankle joints were immobilized unilaterally in the neutral positions. Oxygen uptake was measured using a modified Douglas-bag technique. Heart rate, respiratory rate, and step frequency were telemetered...

INTRODUCTION An unusual situation in which a below knee cast was removed after 28 months is reported. To the best of our knowledge no similar cases have been reported in the literature. CASE PRESENTATION The cast was removed from the leg of a 45-year-old Caucasian woman. Significant muscle atrophy and dense skin scales were present but the underlying skin surface was relatively healthy with o...

Short-term immobilization leads to fatty muscular degeneration, which is associated with various negative health effects. Based on literature showing very high correlations between MRI Dixon fat fraction and Speed-of-Sound (SoS), we hypothesized that can detect short-term-immobilization-induced differences in SoS. Both calves of 10 patients a calf cast one side for mean duration 41 ± 26 days we...