The adhesive proteins employed by mussels have very specialized amino acid compositions undoubtedly related to the particular challenges of achieving permanent adhesion in the wet marine environment. Mussel adhesive proteins (MAPs) are known to contain high levels of the catecholic amino acid 3,4-dihydroxy-L-alanine (DOPA). Catechols are versatile in a chemical sense, participating in redox rea...

Although colorimetry (method of Shaw) permits neither a differentiation of epinephrine and norepinephrine nor their separation from other catechols, it reveals the total urinary catechol excre-tion, including those portions which were inactivated in the body. No significant aklnormalities were found in arterial hypertension, in congestive heart failure, after myocardial infarction and during em...

The relationship of serum dopamine-(-hydroxylase (DBH), plasma renin activity (PRA) and urinary catecholamines (IU catechols) in various forms of essential hypertension (EHT) (low, normal and high renin) was evaluated. Eighty-four predominantly white, young (37 ± 8 years (SD)), mildly hypertensive patients (diastolic pressure 93 ± 4 mm Hg (SD)) continued their regular diet and received no medic...

The relationship of serum dopamine-beta-hydroxylase (DBH), plasma renin activity (PRA) and urinary catecholamines (IU catechols) in various forms of essential hypertension (EHT) (low, normal and high renin) was evaluated. Eighty-four predominantly white, young (37 +/ 8 years (SD)), mildly hypertensive patients (diastolic pressure 93 +/- 4 mm Hg (SD)) continued their regular diet and received no...

The cover illustrates that the monoselective deuteration of diiodomethane mediated by lithium carbenoid is enabled a flow microreactor. monodeuterated obtained was used for protection catechols and Matteson-type homologation to generate single deuterium-labelled molecules. More information can be found in Research Article A. Nagaki co-workers (DOI: 10.1002/chem.202301738).

We have examined the biochemical and histological effects of high concentrations of dopamine (0.05-1.0 micromol) injected into the rat striatum. Twenty-four hours after such injections, the oxidation products of dopamine and dihydroxyphenylacetic acid were detected as both free and protein-bound cysteinyl dopamine and cysteinyl dihydroxyphenylacetic acid. Protein-bound cysteinyl catechols were ...

N-Acetyldopamine (NADA) is the major catechol in the hemolymph of nymphal and adult grasshoppers, Melanoplus sanguinipes (F.), and mainly occurs as an acid-labile conjugate indicated to be a sulfate ester. Its concentration increases in last instar nymphs and peaks during adult cuticle sclerotization. Dopamine (DA), the precursor of NADA and melanic pigments, is about 10 times lower in concentr...